BMRB Entry 52705

Name: FOXO4(86-211) apo form
Published: 2024-12-19

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR52705

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Nicholas Rego and David Koes
3Dmol.js: molecular visualization with WebGL
Bioinformatics (2015) 31 (8): 1322-1324 doi:10.1093/bioinformatics/btu829

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Title:

FOXO4(86-211) apo form

Deposition date:

2024-11-18

Original release date:

2024-12-19

Authors:

Kohoutova, Klara; Srb, Pavel; Obsilova, Veronika; Veverka, Vaclav; Obsil, Tomas

Citation:

Citation: Kohoutova, Klara; Srb, Pavel; Obsilova, Veronika; Veverka, Vaclav; Obsil, Tomas. "Structural Plasticity of the FOXO-DBD:p53-TAD Interaction" Nat. Commun. ., .-..

Assembly members:

Assembly members:
entity_1, polymer, 126 residues, Formula weight is not available

Natural source:

Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens

Experimental source:

Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET-15b

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: GAVTGPRKGGSRRNAWGNQS YAELISQAIESAPEKRLTLA QIYEWMVRTVPYFKDKGDSN SSAGWKNSIRHNLSLHSKFI KVHNEATGKSSWWMLNPEGG KSGKAPRRRAASMDSSSKLL RGRSKA

Data sets:

heteronucl_T1_relaxation
- heteronucl_T1_relaxation_1
heteronucl_T2_relaxation
- heteronucl_T2_relaxation_1

Data type	Count
T1 relaxation values	76
T2 relaxation values	76

Additional metadata:

Assembly
Samples and Experiments
Software
Spectrometers
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Assembly:

Entity Assembly ID	Entity Name	Entity ID
1	FOXO4(86-211)	1

Entities:

Entity 1, FOXO4(86-211) 126 residues - Formula weight is not available

1

GLY

ALA

VAL

THR

GLY

PRO

ARG

LYS

GLY

2

SER

ARG

ASN

ALA

TRP

GLY

ASN

GLN

SER

3

TYR

ALA

GLU

LEU

ILE

SER

GLN

ALA

ILE

GLU

4

SER

ALA

PRO

GLU

LYS

ARG

LEU

THR

LEU

ALA

5

GLN

ILE

TYR

GLU

TRP

MET

VAL

ARG

THR

VAL

6

PRO

TYR

PHE

LYS

ASP

LYS

GLY

ASP

SER

ASN

7

SER

ALA

GLY

TRP

LYS

ASN

SER

ILE

ARG

8

HIS

ASN

LEU

SER

LEU

HIS

SER

LYS

PHE

ILE

9

LYS

VAL

HIS

ASN

GLU

ALA

THR

GLY

LYS

SER

10

SER

TRP

MET

LEU

ASN

PRO

GLU

GLY

11

LYS

SER

GLY

LYS

ALA

PRO

ARG

ALA

12

ALA

SER

MET

ASP

SER

LYS

LEU

13

ARG

GLY

ARG

SER

LYS

ALA

Samples:

sample_1: FOXO4(86-211), [U-100% 15N], 100 uM

sample_conditions_1: ionic strength: 150 mM; pH: 6.5; pressure: 1 atm; temperature: 298 K

Experiments:

Name	Sample	Sample state	Sample conditions
T1/R1 relaxation	sample_1	isotropic	sample_conditions_1
T2/R2 relaxation	sample_1	isotropic	sample_conditions_1

Software:

TOPSPIN v3.6.2 - collection

NMRFAM-SPARKY v3.1 - data analysis

NMR spectrometers:

Bruker AVANCE III 850 MHz