BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 7388

Title: sPLA2 inhibitor pip 17   PubMed: 17973469

Deposition date: 2007-04-20 Original release date: 2008-02-20

Authors: Thwin, M.; Satyanarayanajois, D.; Nagarajarao, L.; Sato, K.; Gopalakrishnakone, P.; Arjunan, P.

Citation: Thwin, M.; Satyanarayanajois, D.; Nagarajarao, L.; Sato, K.; Arjunan, P.; Ramapatna, S.; Kumna, P.; Gopalakrishnakone, P.. "Novel peptide inhibitors of human secretory phospholipase A2 with antiinflammatory activity: solution structure and molecular modeling."  J. Med. Chem. 50, 5938-5950 (2007).

Assembly members:
pip17, polymer, 17 residues, Formula weight is not available

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):
pip17: LGRVDIHVWDGVYIRGR

Data sets:
Data typeCount
1H chemical shifts79

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1pip171

Entities:

Entity 1, pip17 17 residues - Formula weight is not available

1   LEUGLYARGVALASPILEHISVALTRPASP
2   GLYVALTYRILEARGGLYARG

Samples:

sample: pip17 3 mM; dimethylsulfoxide 50%; H2O 50%

sample_conditions_1: ionic strength: . .; pressure: 1 atm; temperature: . K

Experiments:

NameSampleSample stateSample conditions
2D NOESYsampleisotropicsample_conditions_1
2D TOCSYsampleisotropicsample_conditions_1

Software:

CYANA v2.1, GUNTERT, P. ET AL. - refinement

CYANA v2.1, GUNTERT, P. ET AL. - structure solution

NMR spectrometers:

  • Bruker AVANCE 500 MHz

Related Database Links:

PDB
GB AAF73945