Biological Magnetic Resonance Data Bank

A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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Selected Lysozyme Bibliography

Introduction Mechanism Sequence Details BMRB and PDB entries Bibliography

Early Studies

  1. Fleming, A., "On remarkable bacteriolytic element found in tissues and secretions." Proc. Roy. Soc. Series B 93, 306 (1922).
  2. Fleming, A., Allison, V. D. "Observations on a bacteriolytic substance ("lysozyme") found in secretions and tissues." Brit. J. Exp. Path. 13, 252 (1922).
  3. Fleming, A., Allison, V. D. "On the development of strains of bacteria resistant to lysozyme action and the relation of lysozyme action to intracellular digestion." Brit. J. Exp. Path. 8, 214 (1927).
  4. Phillips, D. C. "The three-dimensional structure of an enzyme molecule." Sci. Am. 215(5):78-90 (1966).

NMR Publications

  1. Adriaensens P., Box M. E., Martens H. J., Onkelinx E., Put J., Gelan J. "Investigation of protein structure by means of 19F-NMR. A study of hen egg-white lysozyme." Eur. J. Biochem. 177, 383-94 (1988).
  2. Agresti D. G., Lenkinski R. E., Glickson J. D. "Lanthanide induced NMR perturbations of HEW lysozyme: evidence for nonaxial symmetry." Biochem. Biophys. Res. Commun. 76, 711-9 (1977).
  3. Allerhand, A., Norton, R. S., Childers, R. F. "Studies of Individual Carbon Sites of Hen Egg White Lysozyme by Natural Abundance Carbon 13 Nuclear Magnetic Resonance Spectroscopy." J. Biol. Chem. 252, 1786-94 (1977).
  4. Anderson, D. E., Becktel, W. J., Dahlquist, F. W. "pH-Induced Denaturation of Proteins: A Single Salt Bridge Contributes 3-5 kcal/mol to the Free Energy of Folding of T4 Lysozyme." Biochemistry 29, 2403-8 (1990).
  5. Aramini J. M., Hiraoki T., Ke Y., Nitta K., Vogel H. J. "Cadmium-113 NMR studies of bovine and human alpha-lactalbumin and equine lysozyme." J. Biochem. 117, 623-8 (1995).
  6. Aso, Y., Yoshioka, S., Kojima, S. "Determination of the diffusion coefficient of insulin and lysozyme in crosslinked dextran hydrogels by pulsed-field-gradient NMR." Chem. Pharm. Bull. 46, 1836-9 (1998).
  7. Baguet, E., Hennebert, N. "Characterisation by triple-quantum filtered 17O-NMR of water molecules buried in lysozyme and trapped in a lysozyme-inhibitor complex." Biophys. Biochem. 77, 111-121 (1999).
  8. Bartik, K., Dobson, C. M., Redfield, C. "1H-NMR analysis of turkey egg-white lysozyme and comparison with hen egg-white lysozyme." Eur. J. Biochem. 215, 255-66 (1993).
  9. Bernard, M., Canioni, P., Cozzone, P., Berthou, J., Jolles, P. "Effect of inhibitors on conformational changes in hen lysozyme around thermal transition point in solution and solid state." Int. J. Pept. Protein Res. 36, 46-55 (1990).
  10. Bernard, M., Canioni, P., Cozzone, P., Berthou, J., Jolles, P. "NMR study of conformational changes in lysozyme around the thermal transition point." Int. J. Pept. Protein Res. 27, 643-52 (1986).
  11. Boyd, J., Dobson, C. M., Redfield, C. "Assignment of resonances in the 1H NMR spectrum of human lysozyme." Eur. J. Biochem. 153, 383-96 (1985).
  12. Buck, M., Boyd, J., Redfield, C., MacKenzie, D. A., Jeenes, D. J., Archer, D. B., Dobson, C. M. "Structural determinants of protein dynamics: analysis of 15N NMR relaxation measurements for main-chain and side-chain nuclei of hen egg white lysozyme." Biochemistry 34, 4041-55 (1995).
  13. Buck, M., Schwalbe, H., Dobson, C. M. "Characterization of conformational preferences in a partly folded protein by heteronuclear NMR spectroscopy: assignment and secondary structure analysis of hen egg-white lysozyme in trifluoroethanol." Biochemistry 34, 13219-32 (1995).
  14. Buck, M., Schwalbe, H., Dobson, C. M. "Main-chain dynamics of a partially folded protein: 15N NMR relaxation measurements of hen egg white lysozyme denatured in trifluoroethanol." J. Mol. Biol. 257, 669-83 (1996).
  15. Butchard, C. G., Dwek, R. A., Ferguson, S. J., Kent, P. W., Williams, R. J., Xavier, A. V. "Mapping of the binding site of N-fluoroacetyl-D-glucosamine and analogues in hen egg lysozyme by 1H and 19F-NMR techniques with Gd(III) and Mn(II) as paramagnetic probes." FEBS Lett. 25, 91-3 (1972).
  16. Cassels, R., Dobson, C. M., Poulsen, F. M., Williams, R. J. P. "Study of Tryptophan Residues of Lysozyme Using 1H Nuclear Magnetic Resonance." Eur. J. Biochem. 92, 81-97 (1978).
  17. Chamberlain, A. K., Receveur, V., Spencer, A., Redfield, C., Dobson, C. M. "Characterization of the Structure and Dynamics of Amyloidogenic Variants of Human Lysozyme by NMR Spectroscopy." Protein Sci. 10, 2525-30 (2001).
  18. Collins, E. S., Wirmer, J., Hirai, K., Tachibana, H., Segawa, S., Dobson, C. M., Schwalbe, H. "Characterisation of disulfide-bond dynamics in non-native states of lysozyme and its disulfide deletion mutants by NMR." Chembiochem. 6, 1619-27 (2005).
  19. Datta, G., Gurnani, S., Suryaprakash, N., Ramanathan, K. V., Khetrapal, C.L. "An NMR study of the interaction of cytosine arabinoside and lysozyme." FEBS Lett. 148, 276-80 (1982).
  20. Davis, D. G. "Proton NMR Detection of Long-Range Heteronuclear Multiquantum Coherences in Proteins: The Complete Assignment of the Quaternary Aromatic 13C Shifts in Lysozyme." J. Am. Chem. Soc. 111, 5466-5468 (1989).
  21. Delepierre, M., Dobson, C. M., Howarth, M. A., Poulsen, F. M. "Identification using 1H NMR spectroscopy of slowly exchanging amide hydrogens of hen lysozyme in solution." Eur. J. Biochem. 145, 389-95 (1984).
  22. Delepierre, M., Dobson, C. M., Poulsen, F. M. "Studies of beta-Sheet Structure in Lysozyme by Proton Nuclear Magnetic Resonance. Assignments and Analysis of Spin-Spin Coupling Constants." Biochemistry 21, 4756-61 (1982).
  23. Desvaux, H., Dubois, L., Huber, G., Quillin, M. L., Berthault, P., Matthews, B. W. "Dynamics of xenon binding inside the hydrophobic cavity of pseudo-wild-type bacteriophage T4 lysozyme explored through xenon-based NMR spectroscopy." J. Am. Chem. Soc. 127, 11676-83 (2005).
  24. Dobson, C..M., Williams, R. J. "An NMR study of the dynamics of inhibitor-induced conformational changes in lysozyme." FEBS Lett. 56, 362-5 (1975).
  25. Dobson, C. M. "NMR spectroscopy and protein folding: studies of lysozyme and alpha-lactalbumin." Ciba. Found. Symp. 161, 167-89 (1991)
  26. Dobson, C. M., Evans, P. A., Williamson, K. L. "Proton NMR studies of denatured lysozyme." FEBS Lett. 168, 331-4 (1984).
  27. Dobson, C. M., Ferguson, S. J., Poulsen, F. M., Williams, R. J. P. "Complete Assignment of Aromatic 1H Nuclear Magnetic Resonances of the Tyrosine Residues of Hen Lysozyme." Eur. J. Biochem. 92, 99-103 (1978).
  28. Duewel, H., Daub, E., Robinson, V., Honek, J. F. "Incorporation of trifluoromethionine into a phage lysozyme: implications and a new marker for use in protein 19F NMR." Biochemistry 36, 3404-16 (1997).
  29. Evans, P. A., Topping, K. D., Woolfson, D. N., Dobson, C. M. "Hydrophobic Clustering in Nonnative States of a Protein: Interpretation of Chemical Shifts in NMR Spectra of Denatured States of Lysozyme." Proteins: Struct. Funct. Genet. 9, 248-66 (1991).
  30. Fischer, M. W., Majumdar, A., Dahlquist, F. W., Zuiderweg, E. R. "15N, 13C, and 1H NMR assignments and secondary structure for T4-lysozyme." J. Magn. Reson. B. 108, 143-54 (1995).
  31. Fukamizo, T., Ikeda, Y., Ohkawa, T., Goto, S. "1H-NMR study on the chitotrisaccharide binding to hen egg white lysozyme." Eur. J. Biochem. 210, 351-7 (1992).
  32. Fukamizo, T., Ikeda, Y., Torikata, T., Araki, T., Kuramoto, M., Goto, S. "1H-NMR study on the structure of lysozyme from guinea hen egg white." J. Biochem. 110, 997-1003 (1991).
  33. Fukamizo, T., Yamaguchi, T., Araki, T., Torikata, T., Kristiansen, A., Varum, K. M. "Binding of a highly de-N-acetylated chitosan to Japanese pheasan lysozyme as measured by 1H-NMR spectroscopy." Biosci. Biotechnol. Biochem. 65, 1766-73 (2001).
  34. Fullerton, G. D., Ord, V. A., Cameron, I. L. "An evaluation of the hydration of lysozyme by an NMR titration method." Biochim. Biophys. Acta. 869, 230-46 (1986).
  35. Goto, N. K., Skrynnikov, N. R., Dahlquist, F. W., Kay, L. E. "What is the average conformation of bacteriophage T4 lysozyme in solution? A domain orientation study using dipolar couplings measured by solution NMR." J. Mol. Biol. 308, 745-64 (2001).
  36. Gregory, R. B., Gangoda, M., Gilpin, R. K., Su, W. "The influence of hydration on the conformation of lysozyme studied by solid-state 13C-NMR spectroscopy." Biopolymers 33, 513-9 (1993).
  37. Haliloglu, T., Bahar, I. "Structure-based analysis of protein dynamics: comparison of theoretical results for hen lysozyme with X-ray diffraction and NMR relaxation data." Proteins 37, 654-67 (1999).
  38. Hennig, M., Bermel, W., Spencer, A., Dobson, C. M., Smith, L. J., Schwalbe, H. "Side-chain conformations in an unfolded protein: chi1 distributions in denatured hen lysozyme determined by heteronuclear 13C, 15N NMR spectroscopy." J. Mol Biol. 288, 705-23 (1999).
  39. Ishiguro, K., Yoshie, N., Sakurai, M., Inoue, Y. "A 1H NMR study of a fragment of partially n-acetylated chitin produced by lysozyme degradation." Carbohydr. Res. 237, 333-8 (1992).
  40. Ito, W., Nishimura, M., Sakato, N., Fujio, H., Arata, Y. "A 1H NMR method for the analysis of antigen-antibody interactions: binding of a peptide fragment of lysozyme to anti-lysozyme monoclonal antibody." J. Biochem. 102, 643-9 (1987).
  41. Izumi, T., Yoshimura, Y., Inoue, H. "Solvation of lysozyme in water/dioxane mixtures studied in the frozen state by NMR spectroscopy." Arch. Biochem. Biophys. 200, 444-51 (1980).
  42. Kamatari, Y. O., Yamada, H., Akasaka, K., Jones, J. A., Dobson, C. M., Smith, L. J. "Response of native and denatured hen lysozyme to high pressure studied by (15)N/(1)H NMR spectroscopy." Eur. J. Biochem. 268, 1782-93 (2001).
  43. Kennedy, S. D., Bryant, R. G. "Structural effects of hydration: studies of lysozyme by 13C solids NMR." Biopolymers 29, 1801-6 (1990).
  44. Knubovets, T., Osterhout, J. J., Klibanov, A. M. "Structure of lysozyme dissolved in neat organic solvents as assessed by NMR and CD spectroscopies." Biotechnol. Bioeng. 63, 242-8 (1999).
  45. Kobashigawa, Y., Miura, K., Demura, M., Nemoto, N., Koshiba, T., Nitta, K., Tsuda, S. "Letter to the Editor: Assignment of 1H, 13C, and 15N Resonances of Canine Milk Lysozyme." J. Biomol. NMR 19, 387-8 (2001).
  46. Kristiansen, A., Varum, K. M., Grasdalen, H. "Competitive binding of highly de-N-acetylated chitosans and N,N'-diacetylchitobiose to lysozyme from chicken egg white studied by 1H NMR spectroscopy." Carbohydr. Res. 289, 143-50 (1996).
  47. Kristiansen, A., Varum, K. M., Grasdalen, H. "The interactions between highly de-N-acetylated chitosans and lysozyme from chicken egg white studied by 1H-NMR spectroscopy." Eur. J. Biochem. 251, 335-42 (1998).
  48. Kumeta, H., Kobashigawa, Y., Miura, K., Nishimiya, Y., Oka, C., Nemoto, N., Miura, A., Nitta, K., Tsuda, S. "Letter to the Editor: Assignments of 1H, 13C and 15N Resonances of Human Lysozyme at 4 degrees C." J. Biomol. NMR 22, 183-4 (2002).
  49. Kumeta, H., Miura, A., Kobashigawa, Y., Miura, K., Oka, C., Nemoto, N., Nitta, K., Tsuda, S. "Low-temperature-induced structural changes in human lysozyme elucidated by three-dimensional NMR spectroscopy." Biochemistry 42, 1209-16 (2003).
  50. Liepinsh, E., Genereux, C., Dehareng, D., Joris, B., Otting, G. "NMR structure of Citrobacter freundii AmpD, comparison with bacteriophage T7 lysozyme and homology with PGRP domains." J. Mol. Biol. 327, 833-42 (2003).
  51. Lu, J., Dahlquist, F. W. "Detection and characterization of an early folding intermediate of T4 lysozyme using pulsed hydrogen exchange and two-dimensional NMR." Biochemistry 31, 4749-56 (1992).
  52. Lumb, K. J., Aplin, R. T., Radford, S. E., Archer, D. B., Jeenes, D. J., Lambert, N., MacKenzie, D. A., Dobson, C. M., Lowe, G. "A study of D52S hen lysozyme-GlcNAc oligosaccharide complexes by NMR spectroscopy and electrospray mass spectrometry." FEBS Lett. 296, 153-7 (1992).
  53. Magnuson, J. A., Magnuson, N. S. "A new NMR technique to study disulfide reduction: comparison of lysozyme and -lactalbumin." Biochem. Biophys. Res. Commun. 45, 1513-7 (1971).
  54. McIntosh, L. P., Dahlquist, F. W., Redfield, A. G. "Proton NMR and NOE structural and dynamic studies of larger proteins and nucleic acids aided by isotope labels: T4 lysozyme." J. Biomol. Struct. Dyn. 5, 21-34 (1987).
  55. McIntosh, L. P., Griffey, R. H., Muchmore, D. C., Nielson, C. P., Redfield, A. G., Dahlquist, F. W. "Proton NMR measurements of bacteriophage T4 lysozyme aided by 15N isotopic labeling: structural and dynamic studies of larger proteins." Proc. Natl. Acad. Sci. U. S. A. 84, 1244-8 (1987).
  56. McIntosh, L. P., Wand, A. J., Lowry, D. F., Redfield, A. G., Dahlquist, F. W. "Assignment of the Backbone 1H and 15N NMR Resonances of Bacteriophage T4 Lysozyme." Biochemistry 29, 6341-62 (1990).
  57. McLeish, M. J., Nielsen, K. J., Najbar, L. V., Wade, J. D., Lin, F., Doughty, M. B., Craik, D. J. "Conformation of a peptide corresponding to T4 lysozyme residues 59-81 by NMR and CD spectroscopy." Biochemistry 33, 11174-83 (1994).
  58. Mine, S., Ueda, T., Hashimoto, Y., Imoto, T. "Analysis of the internal motion of free and ligand-bound human lysozyme by use of 15N NMR relaxation measurement: a comparison with those of hen lysozyme." Protein Sci. 9, 1669-84 (2000).
  59. Mine, S., Ueda, T., Hashimoto, Y., Tanaka, Y., Imoto, T. "High-level expression of uniformly 15N-labeled hen lysozyme in Pichia pastoris and identification of the site in hen lysozyme where phosphate ion binds using NMR measurements." FEBS Lett. 448, 33-7 (1999).
  60. Miranker, A., Radford, S. E., Karplus, M., Dobson, C. M. "Demonstration by NMR of folding domains in lysozyme." Nature 349, 633-6 (1991).
  61. Mulder, F. A., Hon, B., Mittermaier, A., Dahlquist, F. W, Kay, L. E. "Slow internal dynamics in proteins: application of NMR relaxation dispersion spectroscopy to methyl groups in a cavity mutant of T4 lysozyme." J. Am. Chem. Soc. 124, 1443-51 (2002).
  62. Mulder, F. A., Hon, B., Muhandiram, D. R., Dahlquist, F. W., Kay, L. E. "Flexibility and ligand exchange in a buried cavity mutant of T4 lysozyme studied by multinuclear NMR." Biochemistry 39, 12614-22 (2000).
  63. Mulder, F. A., Skrynnikov, N. R., Hon, B., Dahlquist, F. W., Kay, L. E. "Measurement of slow (micros-ms) time scale dynamics in protein side chains by (15)N relaxation dispersion NMR spectroscopy: application to Asn and Gln residues in a cavity mutant of T4 lysozyme." J. Am. Chem. Soc. 123, 967-75 (2001).
  64. Nagadome, H., Kawano, K., Terada, Y. "Identification of the adsorbing site of lysozyme onto the hydroxyapatite surface using hydrogen exchange and 1H NMR." FEBS Lett. 317, 128-30 (1993).
  65. Najbar, L. V., Craik, D. J., Wade, J. D., Lin, F., McLeish, M. J. "CD and NMR determination of the solution structure of a peptide corresponding to T4 lysozyme residues 38-51." Biochim. Biophys. Acta. 1250, 163-70 (1995).
  66. Najbar, L. V., Craik, D. J., Wade, J. D., McLeish, M. J. "Identification of initiation sites for T4 lysozyme folding using CD and NMR spectroscopy of peptide fragments." Biochemistry 39, 5911-20 (2000).
  67. Nakazawa, T., Sakiyama, F. "Site-specific 13C-labeling of Trp 62 in hen egg-white lysozyme: preparation and 13C-NMR titration of [delta 1-13C]Trp 62-lysozyme." J. Biochem. 110, 295-300 (1991).
  68. Noda, Y., Fukuda, Y., Segawa, S. "A two-dimensional NMR study of exchange behavior of amide hydrogens in a lysozyme derivative with an extra cross-link between Glu35 and Trp108--quenching of cooperative fluctuations and effects on the Biopolymers 41, 131-43 (1997).
  69. Noda, Y., Yokota, A., Horii, D., Tominaga, T., Tanisaka, Y., Tachibana, H., Segawa, S. "NMR structural study of two-disulfide variant of hen lysozyme: 2SS[6-127, 30-115]--a disulfide intermediate with a partly unfolded structure." Biochemistry 41, 2130-9 (2002).
  70. Obita, T., Ueda, T., Tanaka, Y., Hashimoto, Y., Imoto, T. "Letter to the Editor: Assignment of 1H and 15N resonances of mouse lysozyme M." J. Biomol. NMR 18, 361-2 (2000).
  71. Ohkubo, T., Taniyama, Y., Kikuchi, M. "1H and 15N NMR Study of Human Lysozyme." J. Biochem. 110, 1022-9 (1991).
  72. Ohmura, T., Motoshima, H., Ueda, T., Imoto, T. "Fluctuations in free or substrate-complexed lysozyme and a mutant of it detected on x-ray crystallography and comparison with those detected on NMR." J. Biochem. 131, 701-4 (2002).
  73. Patt, S. L., Dolphin, D., Sykes, B. D. "The detection of substrate distortion by lysozyme: an application of NMR to the study of enzyme substrate reactions." Ann. N. Y. Acad. Sci. 222, 211-9 (1973).
  74. Perkins, S. J., Dwek, R. A. "Comparisons of Ring-Current Shifts Calculated from the Crystal Structure of Egg White Lysozyme of Hen with the Proton Nuclear Magnetic Resonance Spectrum of Lysozyme in Solution." Biochemistry 19, 246-58 (1980).
  75. Perkins, S. J., Johnson, L. N., Phillips, D. C., Dwek, R. A. "Conformational changes, dynamics and assignments in 1H NMR studies of proteins using ring current calculations. Hen egg white lysozyme." FEBS Let. 82, 17-22 (1977).
  76. Pesek, J. J., Schneider, J. F. "The detection of mercury, lead, and methylmercury binding sites on lysozyme by carbon-13 NMR chemical shifts of the carboxylate groups." J. Inorg. Biochem. 32, 233-8 (1988).
  77. Petros, A. M., Kopple, K. D. "NMR studies of protein surfaces. The interaction of lysozyme with tri-N-acetylglucosamine." Biochem. Pharmacol. 40, 65-8 (1990).
  78. Poulsen, F. M., Hoch, J. C., Dobson, C. M. "A Structural Study of the Hydrophobic Box Region of Lysozyme in Solution Using Nuclear Overhauser Effects." Biochemistry 19, 2597-607 (1980).
  79. Poznanski, J., Georgalis, Y., Wehr, L., Zielenkiewicz, P., Saenger, W. "Comparison of Two Different Lysozyme Types Under Native and Crystallization Conditions using Two-Dimensional NMR and Dynamic Light Scattering." BiophysChem. 104, 605-16 (2003)
  80. Price, W. S., Tsuchiya, F., Arata, Y. "Time dependence of aggregation in crystallizing lysozyme solutions probed using NMR self-diffusion measurements." Biophys. J. 80, 1585-90 (2001).
  81. Prosser, S., Peemoeller, H. "Nature of lysozyme-water interactions by proton NMR." Biochem. Cell. Biol. 69, 341-5 (1991).
  82. Redfield, C., Dobson, C. M. "1H NMR studies of human lysozyme: spectral assignment and comparison with hen lysozyme." Biochemistry 29, 7201-14 (1990).
  83. Redfield, C., Dobson, C. M. "Sequential 1H NMR assignments and secondary structure of hen egg white lysozyme in solution." Biochemistry 27, 122-36 (1988).
  84. Redfield, C., Dobson, C. M., Scheek, R. M., Stob, S., Kaptein, R. "Surface accessibility of aromatic residues in human lysozyme using photochemically induced dynamic nuclear polarization NMR spectroscopy." FEBS Let. 185, 248-52 (1985).
  85. Redfield, C., Dobson, C. M. "Sequential 1H NMR Assignments and Secondary Structure of Hen Egg White Lysozyme in Solution." Biochemistry 27, 122-36 (1988).
  86. Redfield, C., Poulsen, F. M., Dobson, C. M. "Complete assignment of the 1H NMR spectrum of the aromatic residues of lysozyme." Eur. J. Biochem. 128, 527-31 (1982).
  87. Rydzy, M., Skrzynski, W. "1H-NMR relaxation studies of native and thermally denatured lysozyme solutions: an isotope dilution experiment." Biochim. Biophys. Acta. 705, 33-7 (1982).
  88. Samarasinghe, S. D., Campbell, D. M., Jonas, A., Jonas, J. "High-resolution NMR study of the pressure-induced unfolding of lysozyme." Biochemistry 31, 7773-8 (1992).
  89. Schwalbe, H., Fiebig, K. M., Buck, M., Jones, J. A., Grimshaw, S. B., Spencer, A., Glaser, S. J., Smith, L. J., Dobson, C. M. "Structural and dynamical properties of a denatured protein. Heteronuclear 3D NMR experiments and theoretical simulations of lysozyme in 8 M urea." Biochemistry 36, 8977-91 (1997).
  90. Schwalbe, H., Grimshaw, S., Spencer, A., Buck, M., Boyd, J., Dobson, C. M., Redfield, C., Smith, L. J. "A Refined Solution Structure of Hen Lysozyme Determined Using Residual Dipolar Coupling Data." Protein Sci. 10, 677-88 (2001).
  91. Segawa, S., Noda, Y., Yokota, A., Tachibana, H. "NMR structural study of disulfide intermediates of hen lysozyme: toward unraveling the protein folding problem" Tanpakushitsu Kakusan Koso 147, 145-51 (2002).
  92. Sheinblatt, M. "NMR studies on the induced denaturation of lysozyme by guanidine hydrochloride in the presence of the inhibitor (NAG)3." Biopolymers 28, 1913-21 (1989).
  93. Skrynnikov, N. R., Mulder, F. A., Hon, B., Dahlquist, F. W., Kay, L. E. "Probing slow time scale dynamics at methyl-containing side chains in proteins by relaxation dispersion NMR measurements: application to methionine residues in a cavity mutant of T4 lysozyme." J. Am. Chem. Soc. 123, 4556-66 (2001).
  94. Smith, L. J., Mark, A. E., Dobson, C. M., van Gunsteren, W. F. "Comparison of MD simulations and NMR experiments for hen lysozyme. Analysis of local fluctuations, cooperative motions, and global changes." Biochemistry 34, 10918-31 (1995).
  95. Smith, L. J., Sutcliffe, M. J., Redfield, C., Dobson, C. M. "Analysis of phi and chi 1 torsion angles for hen lysozyme in solution from 1H NMR spin-spin coupling constants." Biochemistry 30, 989-96 (1991).
  96. Sutcliffe, M. J., Dobson, C. M. "Relaxation data in NMR structure determination: model calculations for the lysozyme-Gd3+ complex." Proteins 10, 117-29 (1991).
  97. Thomas, E. W. "Interaction between diacetylchitobiose methyl glycoside and lysozyme as studied by NMR spectroscopy." Biochem. Biophys. Res. Commun. 29, 628-34 (1967).
  98. Tsuge, H., Koseki, K., Miyano, M., Shimazaki, K., Chuman, T., Matsumoto, T., Noma, M., Nitta, K., Sugai, S. "A structural study of calcium-binding equine lysozyme by two-dimensional 1H-NMR." Biochim. Biophys. Acta. 1078, 77-84 (1991).
  99. Tuzi, S., Shinzawa-Itoh, K., Erata, T., Naito, A., Yoshikawa, S., Saito, H. "A high-resolution solid-state 13C-NMR study on crystalline bovine heart cytochrome-c oxidase and lysozyme. Dynamic behavior of protein and detergent in the complex." Eur. J. Biochem. 208, 713-20 (1992).
  100. Ueda, T., Isakari, Y., Aoki, H., Yasukochi, T., Masutomo, S., Kawano, K., Terada, Y., Yamada, H., Imoto, T. "1H-NMR study of the intramolecular interaction of a substrate analogue covalently attached to aspartic acid-101 in lysozyme." J. Biochem. 109, 690-8 (1991).
  101. Ueda, T., Yamada, H., Sakamoto, N., Abe, Y., Kawano, K., Terada, Y., Imoto, T. "Preparation of a Lysozyme Derivative in Which Two Domains Are Cross-Linked Intramolecularly between Trp62 and Asp101." J. Biochem. 110, 719-25 (1991).
  102. Wang, Y., Bjorndahl, T. C., Wishart, D. S. "Letter to the Editor: Complete 1H and Non-carbonylic 13C Assignments of Native Hen Egg-white Lysozyme." J. Biomol. NMR 17, 83-4 (2000).
  103. Yokota, A., Hirai, K., Miyauchi, H., Iimura, S., Noda, Y., Inoue, K., Akasaka, K., Tachibana, H., Segawa, S. "NMR characterization of three-disulfide variants of lysozyme, C64A/C80A, C76A/C94A, and C30A/C115A--a marginally stable state in folded proteins." Biochemistry 43, 6663-9 (2004).