Lissencephaly
Lissencephaly, which literally means "smooth brain," is a rare, gene-linked brain malformation characterized by the absence of normal convolutions (folds) in the cerebral cortex and an abnormally small head (microcephaly).
Associated Genes
| Gene Name | Chromosome number | BMRB Entries | PDB Entries |
|---|---|---|---|
| DCX | X | BMRB Entries | PDB Entries |
| ISPD | 7 | PDB Entries | |
| NDE1 | 16 |