Lynch syndrome
Lynch syndrome, often called hereditary nonpolyposis colorectal cancer (HNPCC), is an inherited disorder that increases the risk of many types of cancer, particularly cancers of the colon (large intestine) and rectum, which are collectively referred to as colorectal cancer.
Associated Genes
| Gene Name | Chromosome number | BMRB Entries | PDB Entries |
|---|---|---|---|
| MSH2 | 2 | PDB Entries | |
| MSH6 | 2 | PDB Entries | |
| TGFBR2 | 3 | PDB Entries | |
| MLH1 | 3 | PDB Entries | |
| PMS2 | 7 | PDB Entries |