Severe combined immunodeficiency (SCID) is a group of inherited immune system disorders. Infants born with SCID do not gain weight or grow at a healthy rate, which doctors call failure to thrive. An infant with SCID will have a lot of severe bacterial, viral, or fungal infections that often keep coming back after they are treated with drugs.
Gene Name | Chromosome number | BMRB Entries | PDB Entries |
---|---|---|---|
IL7R | 5 | PDB Entries | |
RAG2 | 11 | ||
CD3D | 11 | PDB Entries | |
RAG1 | 11 | BMRB Entries | |
LMO2 | 11 | BMRB Entries | PDB Entries |
JAK3 | 19 | PDB Entries | |
ADA | 20 | BMRB Entries | PDB Entries |