Severe combined immunodeficiency (SCID)
Severe combined immunodeficiency (SCID) is a group of inherited immune system disorders. Infants born with SCID do not gain weight or grow at a healthy rate, which doctors call failure to thrive. An infant with SCID will have a lot of severe bacterial, viral, or fungal infections that often keep coming back after they are treated with drugs.
Associated Genes
| Gene Name | Chromosome number | BMRB Entries | PDB Entries |
|---|---|---|---|
| IL7R | 5 | PDB Entries | |
| RAG2 | 11 | ||
| CD3D | 11 | PDB Entries | |
| RAG1 | 11 | BMRB Entries | |
| LMO2 | 11 | BMRB Entries | PDB Entries |
| JAK3 | 19 | PDB Entries | |
| ADA | 20 | BMRB Entries | PDB Entries |