BMRB Entry 16353

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PDB ID: 2kk6
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR16353
MolProbity Validation Chart

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Title:
SOLUTION STRUCTURE OF SH2 DOMAIN OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FER FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR3461D
Deposition date:
2009-06-15
Original release date:
2009-08-06
Authors:
Tang, Yuefeng; Wang, Dongyan; Nwosu, Chioma; Owens, Leah; Xiao, Rong; Liu, Jinfeng; Baran, Micheal; Swapna, G.V.T; Acton, Thomas; Rost, Burkhard; Montelione, Gaetano
Citation:

Citation: Tang, Yuefeng; Montelione, Gaetano. "SOLUTION STRUCTURE OF SH2 DOMAIN OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FER FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR3461D"  .

Assembly members:

Assembly members:
SH2 domain, polymer, 116 residues, 13645.706 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET 14-15C

Entity Sequences (FASTA):

Entity Sequences (FASTA):
SH2 domain: MGHHHHHHSHMKPLAEQDWY HGAIPRIEAQELLKKQGDFL VRESHGKPGEYVLSVYSDGQ RRHFIIQYVDNMYRFEGTGF SNIPQLIDHHYTTKQVITKK SGVVLLNPIPKDKKWI

Data sets:
Data typeCount
13C chemical shifts500
15N chemical shifts115
1H chemical shifts796

Additional metadata:

  • Assembly
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Assembly:

Entity Assembly IDEntity NameEntity ID
1SH2 domain1

Entities:

Entity 1, SH2 domain 116 residues - 13645.706 Da.

1   METGLYHISHISHISHISHISHISSERHIS
2   METLYSPROLEUALAGLUGLNASPTRPTYR
3   HISGLYALAILEPROARGILEGLUALAGLN
4   GLULEULEULYSLYSGLNGLYASPPHELEU
5   VALARGGLUSERHISGLYLYSPROGLYGLU
6   TYRVALLEUSERVALTYRSERASPGLYGLN
7   ARGARGHISPHEILEILEGLNTYRVALASP
8   ASNMETTYRARGPHEGLUGLYTHRGLYPHE
9   SERASNILEPROGLNLEUILEASPHISHIS
10   TYRTHRTHRLYSGLNVALILETHRLYSLYS
11   SERGLYVALVALLEULEUASNPROILEPRO
12   LYSASPLYSLYSTRPILE

Related Database Links:

PDB 2KK6
DBJ BAG37661 BAG61714 BAJ20192 BAO24701 BAO24702
GB AAA61190 AAI41560 AEY69041 EAW49055 EHH54435
REF NP_001294957 NP_001294960 NP_005237 XP_001099988 XP_001140014
SP P16591
AlphaFold P16591

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