BMRB Entry 16591

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR16591

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Title:
1H and 15N chemical shifts for the immune inhibitory receptor LAIR-1 collagen binding domain
Deposition date:
2009-10-29
Original release date:
2010-02-01
Authors:
Brondijk, Harma; de Ruiter, Talitha; Ballering, Joost; Wienk, Hans; Lebbink, Robert Jan; van Ingen, Hugo; Boelens, Rolf; Farndale, Richard; Meyaard, Linde; Huizinga, Eric
Citation:

Citation: Brondijk, T. Harma C; de Ruiter, Talitha; Ballering, Joost; Wienk, Hans; Lebbink, Robert Jan; van Ingen, Hugo; Boelens, Rolf; Farndale, Richard; Meyaard, Linde; Huizinga, Eric. "Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI."  Blood 115, 1364-1373 (2010).
PubMed: 20007810

Assembly members:

Assembly members:
LAIR-1, polymer, 105 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET3xa

Entity Sequences (FASTA):

Entity Sequences (FASTA):
LAIR-1: SQEEDLPRPSISAEPGTVIP LGSHVTFVCRGPVGVQTFRL ERESRSTYNDTEDVSQASPS ESEARFRIDSVSEGNAGPYR CIYYKPPKWSEQSDYLELLV KEAAA

Data sets:
Data typeCount
15N chemical shifts97
1H chemical shifts567

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1LAIR-11

Entities:

Entity 1, LAIR-1 105 residues - Formula weight is not available

1   SERGLNGLUGLUASPLEUPROARGPROSER
2   ILESERALAGLUPROGLYTHRVALILEPRO
3   LEUGLYSERHISVALTHRPHEVALCYSARG
4   GLYPROVALGLYVALGLNTHRPHEARGLEU
5   GLUARGGLUSERARGSERTHRTYRASNASP
6   THRGLUASPVALSERGLNALASERPROSER
7   GLUSERGLUALAARGPHEARGILEASPSER
8   VALSERGLUGLYASNALAGLYPROTYRARG
9   CYSILETYRTYRLYSPROPROLYSTRPSER
10   GLUGLNSERASPTYRLEUGLULEULEUVAL
11   LYSGLUALAALAALA

Related Database Links:

PDB 3KGR 3RP1
DBJ BAG53543
GB AAF17107 AAF71274 EAW72234 EAW72235 EAW72237
REF XP_011546916

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