BMRB Entry 17287

Name: NMR solution structure ensemble of domain 11 of the echidna M6P/IGF2R receptor
Published: 2012-11-05

Click here to enlarge.

PDB ID: 2lla
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR17287
MolProbity Validation Chart

NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry

Nicholas Rego and David Koes
3Dmol.js: molecular visualization with WebGL
Bioinformatics (2015) 31 (8): 1322-1324 doi:10.1093/bioinformatics/btu829

Select model:

I am color blind

Download raw data. Direct link to this display. Help

Title:

NMR solution structure ensemble of domain 11 of the echidna M6P/IGF2R receptor

Deposition date:

2010-11-09

Original release date:

2012-11-05

Authors:

Strickland, Madeleine; Crump, Matthew; Williams, Christopher; Rezgui, Dellel; Ellis, Rosamund; Hoppe, Hans; Frago, Susana; Prince, Stuart; Zaccheo, Oliver; Forbes, Briony; Jones, E Yvonne; Hassan, A Bassim; Wattana-Amorn, Pakorn

Citation:

Citation: Williams, Christopher; Hoppe, Hans; Rezgui, Dellel; Strickland, Madeline; Frago, Susana; Ellis, Rosamund; Wattana-Amorn, Pakorn; Prince, Stuart; Zaccheo, Oliver; Forbes, Briony; Jones, E.; Crump, Matthew; Hassan, A.; Grutzner, Frank; Nolan, Catherine; Mungall, Andrew. "An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution" Science 338, 1209-1213 (2012).
PubMed: 23197533

Assembly members:

Assembly members:
entity, polymer, 140 residues, 15298.419 Da.

Natural source:

Natural source: Common Name: Australian echidna Taxonomy ID: 9261 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Tachyglossus aculeatus

Experimental source:

Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET26

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity: MVQDNCQVTNPATGYVFDLN SLKRESGYTISDIRKGSIRL GVCGEVKDCGPGIGACFEGT GIKAGKWNQKLSYVDQVLQL VYEDGDPCPANLHLKYKSVI SFVCKSDAGPTSQPLLLSVD EHTCTLFFSWHTSLACEQEV

Data sets:

assigned_chemical_shifts
- assigned_chem_shift_list_1

Data type	Count
13C chemical shifts	585
15N chemical shifts	146
1H chemical shifts	949

Additional metadata:

Assembly
Samples and Experiments
Software
Spectrometers
Hide all

Assembly:

Entity Assembly ID	Entity Name	Entity ID
1	M6P/IGF2_receptor	1

Entities:

Entity 1, M6P/IGF2_receptor 140 residues - 15298.419 Da.

1	MET	VAL	GLN	ASP	ASN	CYS	GLN	VAL	THR	ASN
2	PRO	ALA	THR	GLY	TYR	VAL	PHE	ASP	LEU	ASN
3	SER	LEU	LYS	ARG	GLU	SER	GLY	TYR	THR	ILE
4	SER	ASP	ILE	ARG	LYS	GLY	SER	ILE	ARG	LEU
5	GLY	VAL	CYS	GLY	GLU	VAL	LYS	ASP	CYS	GLY
6	PRO	GLY	ILE	GLY	ALA	CYS	PHE	GLU	GLY	THR
7	GLY	ILE	LYS	ALA	GLY	LYS	TRP	ASN	GLN	LYS
8	LEU	SER	TYR	VAL	ASP	GLN	VAL	LEU	GLN	LEU
9	VAL	TYR	GLU	ASP	GLY	ASP	PRO	CYS	PRO	ALA
10	ASN	LEU	HIS	LEU	LYS	TYR	LYS	SER	VAL	ILE
11	SER	PHE	VAL	CYS	LYS	SER	ASP	ALA	GLY	PRO
12	THR	SER	GLN	PRO	LEU	LEU	LEU	SER	VAL	ASP
13	GLU	HIS	THR	CYS	THR	LEU	PHE	PHE	SER	TRP
14	HIS	THR	SER	LEU	ALA	CYS	GLU	GLN	GLU	VAL

Name	Sample	Sample state	Sample conditions
2D 1H-15N HSQC	sample_1	isotropic	sample_conditions_1
2D 1H-13C HSQC	sample_1	isotropic	sample_conditions_1
3D CBCA(CO)NH	sample_1	isotropic	sample_conditions_1
3D C(CO)NH	sample_1	isotropic	sample_conditions_1
3D HNCO	sample_1	isotropic	sample_conditions_1
3D HNCACB	sample_1	isotropic	sample_conditions_1
3D H(CCO)NH	sample_1	isotropic	sample_conditions_1
3D 1H-15N NOESY	sample_1	isotropic	sample_conditions_1
3D 1H-13C NOESY	sample_1	isotropic	sample_conditions_1
3D HNCA	sample_1	isotropic	sample_conditions_1

BMRB Entry 17287

Additional metadata:

Assembly:

Entities:

Samples:

Experiments:

Software:

NMR spectrometers:

Related Database Links:

1	MET	VAL	GLN	ASP	ASN	CYS	GLN	VAL	THR	ASN
2	PRO	ALA	THR	GLY	TYR	VAL	PHE	ASP	LEU	ASN
3	SER	LEU	LYS	ARG	GLU	SER	GLY	TYR	THR	ILE
4	SER	ASP	ILE	ARG	LYS	GLY	SER	ILE	ARG	LEU
5	GLY	VAL	CYS	GLY	GLU	VAL	LYS	ASP	CYS	GLY
6	PRO	GLY	ILE	GLY	ALA	CYS	PHE	GLU	GLY	THR
7	GLY	ILE	LYS	ALA	GLY	LYS	TRP	ASN	GLN	LYS
8	LEU	SER	TYR	VAL	ASP	GLN	VAL	LEU	GLN	LEU
9	VAL	TYR	GLU	ASP	GLY	ASP	PRO	CYS	PRO	ALA
10	ASN	LEU	HIS	LEU	LYS	TYR	LYS	SER	VAL	ILE
11	SER	PHE	VAL	CYS	LYS	SER	ASP	ALA	GLY	PRO
12	THR	SER	GLN	PRO	LEU	LEU	LEU	SER	VAL	ASP
13	GLU	HIS	THR	CYS	THR	LEU	PHE	PHE	SER	TRP
14	HIS	THR	SER	LEU	ALA	CYS	GLU	GLN	GLU	VAL

1	MET	VAL	GLN	ASP	ASN	CYS	GLN	VAL	THR	ASN
2	PRO	ALA	THR	GLY	TYR	VAL	PHE	ASP	LEU	ASN
3	SER	LEU	LYS	ARG	GLU	SER	GLY	TYR	THR	ILE
4	SER	ASP	ILE	ARG	LYS	GLY	SER	ILE	ARG	LEU
5	GLY	VAL	CYS	GLY	GLU	VAL	LYS	ASP	CYS	GLY
6	PRO	GLY	ILE	GLY	ALA	CYS	PHE	GLU	GLY	THR
7	GLY	ILE	LYS	ALA	GLY	LYS	TRP	ASN	GLN	LYS
8	LEU	SER	TYR	VAL	ASP	GLN	VAL	LEU	GLN	LEU
9	VAL	TYR	GLU	ASP	GLY	ASP	PRO	CYS	PRO	ALA
10	ASN	LEU	HIS	LEU	LYS	TYR	LYS	SER	VAL	ILE
11	SER	PHE	VAL	CYS	LYS	SER	ASP	ALA	GLY	PRO
12	THR	SER	GLN	PRO	LEU	LEU	LEU	SER	VAL	ASP
13	GLU	HIS	THR	CYS	THR	LEU	PHE	PHE	SER	TRP
14	HIS	THR	SER	LEU	ALA	CYS	GLU	GLN	GLU	VAL

1	MET	VAL	GLN	ASP	ASN	CYS	GLN	VAL	THR	ASN
2	PRO	ALA	THR	GLY	TYR	VAL	PHE	ASP	LEU	ASN
3	SER	LEU	LYS	ARG	GLU	SER	GLY	TYR	THR	ILE
4	SER	ASP	ILE	ARG	LYS	GLY	SER	ILE	ARG	LEU
5	GLY	VAL	CYS	GLY	GLU	VAL	LYS	ASP	CYS	GLY
6	PRO	GLY	ILE	GLY	ALA	CYS	PHE	GLU	GLY	THR
7	GLY	ILE	LYS	ALA	GLY	LYS	TRP	ASN	GLN	LYS
8	LEU	SER	TYR	VAL	ASP	GLN	VAL	LEU	GLN	LEU
9	VAL	TYR	GLU	ASP	GLY	ASP	PRO	CYS	PRO	ALA
10	ASN	LEU	HIS	LEU	LYS	TYR	LYS	SER	VAL	ILE
11	SER	PHE	VAL	CYS	LYS	SER	ASP	ALA	GLY	PRO
12	THR	SER	GLN	PRO	LEU	LEU	LEU	SER	VAL	ASP
13	GLU	HIS	THR	CYS	THR	LEU	PHE	PHE	SER	TRP
14	HIS	THR	SER	LEU	ALA	CYS	GLU	GLN	GLU	VAL