BMRB Entry 27729

Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR27729

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Title:
IL37 53-206 dimer
Deposition date:
2018-12-15
Original release date:
2019-01-15
Authors:
Eisenmesser, Elan
Citation:

Citation: Eisenmesser, Elan; Gottschlich, Adrian; Redzic, Jasmina; Paukovich, Natasia; Nix, Jay; Azam, Tania; Zhang, Lingdi; Zhao, Rui; Kieft, Jeffrey; The, Erlinda; Meng, Xianzhong; Dinarello, Charles. "Interleukin-37 monomer is the active form for reducing innate immunity."  Proc. Natl. Acad. Sci. U.S.A. 116, 5514-5522 (2019).
PubMed: 30819901

Assembly members:

Assembly members:
IL37_dimer, polymer, 218 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: E. coli   Taxonomy ID: 562   Superkingdom: Bacteria   Kingdom: not available   Genus/species: Escherichia coli

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET21

Entity Sequences (FASTA):

Entity Sequences (FASTA):
IL37_dimer: MSFVGENSGVKMGSEDWEKD EPQCCLEDPAGSPLEPGPSL PTMNFVHTSPKVKNLNPKKF SIHDQDHKVLVLDSGNLIAV PDKNYIRPEIFFALASSLSS ASAEKGSPILLGVSKGEFCL YCDKDKGQSHPSLQLKKEKL MKLAAQKESARRPFIFYRAQ VGSWNMLESAAHPGWFICTS CNCNEPVGVTDKFENRKHIE FSFQPVCKAEMSPSEVSD

Data sets:
Data typeCount
13C chemical shifts444
15N chemical shifts145
1H chemical shifts249

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1Il37 chain A1
2Il37 chain B1

Entities:

Entity 1, Il37 chain A 218 residues - Formula weight is not available

1   METSERPHEVALGLYGLUASNSERGLYVAL
2   LYSMETGLYSERGLUASPTRPGLULYSASP
3   GLUPROGLNCYSCYSLEUGLUASPPROALA
4   GLYSERPROLEUGLUPROGLYPROSERLEU
5   PROTHRMETASNPHEVALHISTHRSERPRO
6   LYSVALLYSASNLEUASNPROLYSLYSPHE
7   SERILEHISASPGLNASPHISLYSVALLEU
8   VALLEUASPSERGLYASNLEUILEALAVAL
9   PROASPLYSASNTYRILEARGPROGLUILE
10   PHEPHEALALEUALASERSERLEUSERSER
11   ALASERALAGLULYSGLYSERPROILELEU
12   LEUGLYVALSERLYSGLYGLUPHECYSLEU
13   TYRCYSASPLYSASPLYSGLYGLNSERHIS
14   PROSERLEUGLNLEULYSLYSGLULYSLEU
15   METLYSLEUALAALAGLNLYSGLUSERALA
16   ARGARGPROPHEILEPHETYRARGALAGLN
17   VALGLYSERTRPASNMETLEUGLUSERALA
18   ALAHISPROGLYTRPPHEILECYSTHRSER
19   CYSASNCYSASNGLUPROVALGLYVALTHR
20   ASPLYSPHEGLUASNARGLYSHISILEGLU
21   PHESERPHEGLNPROVALCYSLYSALAGLU
22   METSERPROSERGLUVALSERASP

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SPARKY: Backbone or all simulated peaks