BMRB Entry 5474
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR5474
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Citation: Meier, Sebastian; Li, Yu-Chin; Koehn, James; Vlattas, Isidoros; Wareing, James; Jahnke, Wolfgang; Wennogle, Lawrence; Grzesiek, Stephan. "Letter to the Editor: Backbone resonance assignment of the 298 amino acid
catalytic domain of protein tyrosine phosphatase 1B (PTP1B)" J. Biomol. NMR 24, 165-166 (2002).
Assembly members:
protein tyrosine phosphatase 1B, polymer, 298 residues, 34672 Da.
DADEXLIP-amide,(X=phenylalanine-p-difluoromethyl phosphonate), polymer, 8 residues, 34672 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET 19-b
Entity Sequences (FASTA):
protein tyrosine phosphatase 1B: MEMEKEFEQIDKSGSWAAIY
QDIRHEASDFPCRVAKLPKN
KNRNRYRDVSPFDHSRIKLH
QEDNDYINASLIKMEEAQRS
YILTQGPLPNTCGHFWEMVW
EQKSRGVVMLNRVMEKGSLK
CAQYWPQKEEKEMIFEDTNL
KLTLISEDIKSYYTVRQLEL
ENLTTQETREILHFHYTTWP
DFGVPESPASFLNFLFKVRE
SGSLSPEHGPVVVHCSAGIG
RSGTFCLADTCLLLMDKRKD
PSSVDIKKVLLEMRKFRMGL
IQTADQLRFSYLAVIEGAKF
IMGDSSVQDQWKELSHED
DADEXLIP-amide,(X=phenylalanine-p-difluoromethyl phosphonate): DADEXLIP
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 218 |
| 13C chemical shifts | 697 |
| 15N chemical shifts | 218 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | protein tyrosine phosphatase 1B | 1 |
| 2 | DADEXLIP-amide,(X=phenylalanine-p-difluoromethyl phosphonate) | 2 |
Entities:
Entity 1, protein tyrosine phosphatase 1B 298 residues - 34672 Da.
| 1 | MET | GLU | MET | GLU | LYS | GLU | PHE | GLU | GLN | ILE | ||||
| 2 | ASP | LYS | SER | GLY | SER | TRP | ALA | ALA | ILE | TYR | ||||
| 3 | GLN | ASP | ILE | ARG | HIS | GLU | ALA | SER | ASP | PHE | ||||
| 4 | PRO | CYS | ARG | VAL | ALA | LYS | LEU | PRO | LYS | ASN | ||||
| 5 | LYS | ASN | ARG | ASN | ARG | TYR | ARG | ASP | VAL | SER | ||||
| 6 | PRO | PHE | ASP | HIS | SER | ARG | ILE | LYS | LEU | HIS | ||||
| 7 | GLN | GLU | ASP | ASN | ASP | TYR | ILE | ASN | ALA | SER | ||||
| 8 | LEU | ILE | LYS | MET | GLU | GLU | ALA | GLN | ARG | SER | ||||
| 9 | TYR | ILE | LEU | THR | GLN | GLY | PRO | LEU | PRO | ASN | ||||
| 10 | THR | CYS | GLY | HIS | PHE | TRP | GLU | MET | VAL | TRP | ||||
| 11 | GLU | GLN | LYS | SER | ARG | GLY | VAL | VAL | MET | LEU | ||||
| 12 | ASN | ARG | VAL | MET | GLU | LYS | GLY | SER | LEU | LYS | ||||
| 13 | CYS | ALA | GLN | TYR | TRP | PRO | GLN | LYS | GLU | GLU | ||||
| 14 | LYS | GLU | MET | ILE | PHE | GLU | ASP | THR | ASN | LEU | ||||
| 15 | LYS | LEU | THR | LEU | ILE | SER | GLU | ASP | ILE | LYS | ||||
| 16 | SER | TYR | TYR | THR | VAL | ARG | GLN | LEU | GLU | LEU | ||||
| 17 | GLU | ASN | LEU | THR | THR | GLN | GLU | THR | ARG | GLU | ||||
| 18 | ILE | LEU | HIS | PHE | HIS | TYR | THR | THR | TRP | PRO | ||||
| 19 | ASP | PHE | GLY | VAL | PRO | GLU | SER | PRO | ALA | SER | ||||
| 20 | PHE | LEU | ASN | PHE | LEU | PHE | LYS | VAL | ARG | GLU | ||||
| 21 | SER | GLY | SER | LEU | SER | PRO | GLU | HIS | GLY | PRO | ||||
| 22 | VAL | VAL | VAL | HIS | CYS | SER | ALA | GLY | ILE | GLY | ||||
| 23 | ARG | SER | GLY | THR | PHE | CYS | LEU | ALA | ASP | THR | ||||
| 24 | CYS | LEU | LEU | LEU | MET | ASP | LYS | ARG | LYS | ASP | ||||
| 25 | PRO | SER | SER | VAL | ASP | ILE | LYS | LYS | VAL | LEU | ||||
| 26 | LEU | GLU | MET | ARG | LYS | PHE | ARG | MET | GLY | LEU | ||||
| 27 | ILE | GLN | THR | ALA | ASP | GLN | LEU | ARG | PHE | SER | ||||
| 28 | TYR | LEU | ALA | VAL | ILE | GLU | GLY | ALA | LYS | PHE | ||||
| 29 | ILE | MET | GLY | ASP | SER | SER | VAL | GLN | ASP | GLN | ||||
| 30 | TRP | LYS | GLU | LEU | SER | HIS | GLU | ASP |
Entity 2, DADEXLIP-amide,(X=phenylalanine-p-difluoromethyl phosphonate) 8 residues - 34672 Da.
| 1 | ASP | ALA | ASP | GLU | X | LEU | ILE | PRO |
Related Database Links:
| SWISS-PROT | P18031 |
| REF | XP_001096412 XP_001096290 XP_001096168 XP_001096053 NP_002818 |
| GenBank | AAP35398 AAH18164 AAH15660 AAA60223 AAA60157 |
| EMBL | CAI23215 CAH90487 CAC00618 |
| DBJ | BAG61697 BAG38152 BAG11007 BAF83327 |
| PDB | 3CWE 2VEY 2VEX 2VEW 2VEV 2VEU 2QBS 2QBR 2QBQ 2QBP 2NTA 2NT7 2HNQ 2HNP 2HB1 2H4K 2H4G 2FJN 2FJM 2F71 2F70 2F6Z 2F6Y 2F6W 2F6V 2F6T 2F6F 2CNI 2CNH 2CNG 2CNF 2CNE 2CMC 2CMB 2CMA 2CM8 2CM7 2CM3 2CM2 2BGE 2BGD 2B4S 2B07 2AZR 1XBO 1WAX 1T4J 1T49 1T48 1SUG 1QXK 1Q6T 1Q6S 1Q6P 1Q6N 1Q6M 1Q6J 1Q1M 1PYN 1PXH 1PTY 1PTV 1PTU 1PTT 1PH0 1PA1 1ONZ 1ONY 1OEV 1OEU 1OET 1OES 1OEO 1OEM 1NZ7 1NWL 1NWE 1NO6 1NNY 1NL9 1LQF 1L8G 1KAV 1KAK 1JF7 1I57 1G7G 1G7F 1G1H 1G1G 1G1F 1EEO 1EEN 1ECV 1C88 1C87 1C86 1C85 1C84 1C83 1BZJ 1BZH 1BZC 1AAX 1A5Y |
Download HSQC peak lists in one of the following formats:
CSV: Backbone
or all simulated peaks
SPARKY: Backbone
or all simulated peaks