BMRB Entry 15095

Title:
Solution Structure of a Dodecapeptide from Alpha-Synuclein Bound with Synphilin-1
Deposition date:
2007-01-04
Original release date:
2009-09-29
Authors:
Zhou, Chen-Jie; Hu, Hong-Yu; Lin, Dong-Hai
Citation:

Citation: Xie, Yuan-Yuan; Zhou, Chen-Jie; Zhou, Zi-Ren; Hong, Jing; Che, Mei-Xia; Fu, Qing-Shan; Song, Ai-Xin; Lin, Dong-Hai; Hu, Hong-Yu. "Interaction with synphilin-1 promotes inclusion formation of alpha-synuclein: mechanistic insights and pathological implication."  FASEB J. 24, 196-205 (2010).
PubMed: 19762560

Assembly members:

Assembly members:
Alpha-Syn12, polymer, 12 residues, 1357.708 Da.
Synphilin, non-polymer, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Alpha-Syn12: MDVFMKGLSKAK

Data sets:
Data typeCount
1H chemical shifts73

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1Alpha-Syn121
2Synphilin-12

Entities:

Entity 1, Alpha-Syn12 12 residues - 1357.708 Da.

1   METASPVALPHEMETLYSGLYLEUSERLYS
2   ALALYS

Entity 2, Synphilin-1 - . - Formula weight is not available

1   Synphilin