BMRB Entry 17394

Title:
Solution NMR structure of human amylin in SDS micelles at pH 7.3
Deposition date:
2011-01-04
Original release date:
2012-06-19
Authors:
Nanga, Ravi Prakash Reddy; Brender, Jeffrey; Vivekanandan, Subramanian; Ramamoorthy, Ayyalusamy
Citation:

Citation: Nanga, Ravi Prakash Reddy; Brender, Jeffrey; Vivekanandan, Subramanian; Ramamoorthy, Ayyalusamy. "Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment."  Biochim. Biophys. Acta 1808, 2337-2342 (2011).
PubMed: 21723249

Assembly members:

Assembly members:
entity, polymer, 37 residues, 3909.330 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: obtained from a vendor

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity: KCNTATCATQRLANFLVHSS NNFGAILSSTNVGSNTY

Data sets:
Data typeCount
1H chemical shifts228

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1amidated IAPP1

Entities:

Entity 1, amidated IAPP 37 residues - 3909.330 Da.

1   LYSCYSASNTHRALATHRCYSALATHRGLN
2   ARGLEUALAASNPHELEUVALHISSERSER
3   ASNASNPHEGLYALAILELEUSERSERTHR
4   ASNVALGLYSERASNTHRTYR

Related Database Links:

BMRB 16104 16105 18795 20045
PDB 2G48 2KB8 2L86 3G7V 3G7W 3HGZ
DBJ BAG73319
EMBL CAA33032 CAA37002 CAA39504 CAA48724 CAB57803
GB AAA35524 AAA35983 AAA51728 AAA52281 AAI11850
REF NP_000406 XP_001144800 XP_003265632 XP_003265633 XP_003828947
SP P10997
AlphaFold P10997