BMRB Entry 17424

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PDB ID: 2l8s
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR17424
MolProbity Validation Chart

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Title:
Solution NMR Structure of Transmembrane and Cytosolic Regions of Integrin 1 in Detergent Micelles
Deposition date:
2011-01-24
Original release date:
2012-08-14
Authors:
Lai, Chaohua; Liu, Xiaoxi; Tian, Changlin
Citation:

Citation: Lai, Chaohua; Liu, Xiaoxi; Tian, Changlin; Wu, Fangming. "Integrin 1 has a long helix, extending from the transmembrane region to the cytoplasmic tail in detergent micelles."  PLoS ONE 8, e62954-e62954 (2013).
PubMed: 23646163

Assembly members:

Assembly members:
Integrin_Alpha1, polymer, 54 residues, 5272.820 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET21b

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Integrin_Alpha1: MGLPGRVPLWVILLSAFAGL LLLMLLILALWKIGFFKRPL KKKMEKLEHHHHHH

Data sets:
Data typeCount
13C chemical shifts176
15N chemical shifts38
1H chemical shifts202

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1Integrin_Alpha11

Entities:

Entity 1, Integrin_Alpha1 54 residues - 5272.820 Da.

1   METGLYLEUPROGLYARGVALPROLEUTRP
2   VALILELEULEUSERALAPHEALAGLYLEU
3   LEULEULEUMETLEULEUILELEUALALEU
4   TRPLYSILEGLYPHEPHELYSARGPROLEU
5   LYSLYSLYSMETGLULYSLEUGLUHISHIS
6   HISHISHISHIS

Related Database Links:

PDB 2L8S
DBJ BAC35370 BAE20498 BAG62150
EMBL CAA36384
GB AAI37122 AAI37123 AAI67237 EAW54865 EAW54868
REF NP_001028400 NP_001296395 NP_112256 NP_852478 XP_001094788
SP P18614 P56199 Q3V3R4
TPG DAA17923
AlphaFold P18614 P56199 Q3V3R4

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