BMRB Entry 17558

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PDB ID: 2lbg
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR17558
MolProbity Validation Chart

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Title:
Structure of the CHR of the Prion protein in DPC Micelles
Deposition date:
2011-03-31
Original release date:
2011-12-05
Authors:
Sauve, Simon; Aubin, Yves
Citation:

Citation: Sauve, Simon; Buijs, Daniel; Gingras, Genevieve; Aubin, Yves. "Interactions between the Conserved Hydrophobic Region of the Prion Protein and Dodecylphosphocholine Micelles."  J. Biol. Chem. 287, 1915-1922 (2012).
PubMed: 22128151

Assembly members:

Assembly members:
PrP_Conserved_Hydrophobic_Domain, polymer, 27 residues, Formula weight is not available
DPV, non-polymer, 351.462 Da.

Natural source:

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET19b-GST

Entity Sequences (FASTA):

Entity Sequences (FASTA):
PrP_Conserved_Hydrophobic_Domain: KHMAGAAAAGAVVGGLGGYM LGSAMSR

Data sets:
Data typeCount
13C chemical shifts90
15N chemical shifts25
1H chemical shifts141

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1peptide1
2micelle2

Entities:

Entity 1, peptide 27 residues - Formula weight is not available

Residues 1-27 represents the sequence 110-136 in the mature polypeptide sequence of the human PrP protein

1   LYSHISMETALAGLYALAALAALAALAGLY
2   ALAVALVALGLYGLYLEUGLYGLYTYRMET
3   LEUGLYSERALAMETSERARG

Entity 2, micelle - C17 H38 N O4 P - 351.462 Da.

1   DPV

Related Database Links:

BMRB 16743 17034 17714 17756 17757 17780 18426 18550 19268 4307 4402 4434 4641
PDB 1B10 1FKC 1FO7 1I4M 1QLX 1QLZ 1QM0 1QM1 1XYJ 1XYK 1XYQ 1XYU 1XYW 1XYX 1Y15 1Y16 2KUN 2LBG 2LEJ 2LFT 2LSB 2LV1 2M8T 2W9E 3HEQ 3HES 4DGI 4H88 4HLS 4HMM 4HMR 4KML 4N9O 4YXK 4YXL
DBJ BAD51981 BAE91721 BAF62360 BAG32276 BAG32278
EMBL CAA58442 CAH92912
GB AAA37014 AAA37090 AAA37091 AAA37092 AAA37093
PIR B34759
REF NP_000302 NP_001009093 NP_001040617 NP_001073590 NP_001073591
SP O18754 P04156 P04273 P40245 P40246
TPE CAJ43807 CAJ43808
AlphaFold O18754 P04156 P04273 P40245 P40246

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