BMRB Entry 17691

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PDB ID: 2le4
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR17691
MolProbity Validation Chart

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Title:
Solution structure of the HMG box DNA-binding domain of human stem cell transcription factor Sox2
Deposition date:
2011-06-06
Original release date:
2011-07-06
Authors:
Sahu, Sarata; Markley, John; Tonelli, Marco; Bahrami, Arash; Eghbalnia, Hamid
Citation:

Citation: Sahu, Sarata; Markley, John; Tonelli, Marco; Bahrami, Arash; Eghbalnia, Hamid. "Not known"  .

Assembly members:

Assembly members:
Sox2, polymer, 81 residues, 9920.689 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pEU-HIS

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Sox2: SDRVKRPMNAFMVWSRGQRR KMAQENPKMHNSEISKRLGA EWKLLSETEKRPFIDEAKRL RALHMKEHPDYKYRPRRKTK T

Data sets:
Data typeCount
13C chemical shifts370
15N chemical shifts80
1H chemical shifts532

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
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Assembly:

Entity Assembly IDEntity NameEntity ID
1Sox21

Entities:

Entity 1, Sox2 81 residues - 9920.689 Da.

1   SERASPARGVALLYSARGPROMETASNALA
2   PHEMETVALTRPSERARGGLYGLNARGARG
3   LYSMETALAGLNGLUASNPROLYSMETHIS
4   ASNSERGLUILESERLYSARGLEUGLYALA
5   GLUTRPLYSLEULEUSERGLUTHRGLULYS
6   ARGPROPHEILEASPGLUALALYSARGLEU
7   ARGALALEUHISMETLYSGLUHISPROASP
8   TYRLYSTYRARGPROARGARGLYSTHRLYS
9   THR

Related Database Links:

PDB 1GT0 1O4X 2LE4
DBJ BAA09168 BAC55017 BAC67545 BAC75668 BAE20882
EMBL CAA63847 CAA65725 CAA80631 CAA83435 CAF91617
GB AAA35997 AAB09662 AAB62821 AAC14215 AAC31791
PRF 1612347C
REF NP_001081691 NP_001098933 NP_001102651 NP_001116669 NP_001135190
SP O42569 P48430 P48431 P48432 P54231
TPG DAA33313
AlphaFold O42569 P48430 P48431 P48432 P54231