BMRB Entry 18498
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PDB ID: 2ltv
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR18498
MolProbity Validation Chart
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NMR-STAR v3 text file.
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Citation: Aragon, Eric; Goerner, Nina; Xi, Qiaoran; Gomes, Tiago; Gao, Sheng; Massague, Joan; Macias, Maria. "Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways" Structure 20, 1726-1736 (2012).
PubMed: 22921829
Assembly members:
YAPWW2, polymer, 36 residues, 4191.631 Da.
SMAD7, polymer, 12 residues, 1407.580 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: petM11
Entity Sequences (FASTA):
YAPWW2: GPLPDGWEQAMTQDGEIYYI
NHKNKTTSWLDPRLDP
SMAD7: GSPPPPYSRYPMD
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 279 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | YAP WW2 | 1 |
| 2 | Smad7 derived peptide | 2 |
Entities:
Entity 1, YAP WW2 36 residues - 4191.631 Da.
| 1 | GLY | PRO | LEU | PRO | ASP | GLY | TRP | GLU | GLN | ALA | ||||
| 2 | MET | THR | GLN | ASP | GLY | GLU | ILE | TYR | TYR | ILE | ||||
| 3 | ASN | HIS | LYS | ASN | LYS | THR | THR | SER | TRP | LEU | ||||
| 4 | ASP | PRO | ARG | LEU | ASP | PRO |
Entity 2, Smad7 derived peptide 12 residues - 1407.580 Da.
| 1 | GLY | SER | PRO | PRO | PRO | PRO | TYR | SER | ARG | TYR | ||||
| 2 | PRO | MET | ASP |
Related Database Links:
| BMRB | 17538 |
| PDB | 2LAW 2LTV |
| DBJ | BAG62143 BAH14487 |
| EMBL | CCI79621 CCI79622 |
| GB | EAW67013 ELW64947 EMP37969 ETE73276 KFP99983 |
| REF | NP_001181974 XP_002822438 XP_003253086 XP_004052073 XP_004283405 |
| AlphaFold | Q6DK23 |