BMRB Entry 18499
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PDB ID: 2ltw
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR18499
MolProbity Validation Chart
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NMR-STAR v3 text file.
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Citation: Aragon, Eric; Goerner, Nina; Xi, Qiaoran; Gomes, Tiago; Gao, Sheng; Massague, Joan; Macias, Maria. "Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways" Structure 20, 1726-1736 (2012).
PubMed: 22921829
Assembly members:
YAPWW1, polymer, 36 residues, 4151.635 Da.
SMAD7, polymer, 14 residues, 1593.747 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: petM11
Entity Sequences (FASTA):
YAPWW1: DVPLPAGWEMAKTSSGQRYF
LNHIDQTTTWQDPRKA
SMAD7: GESPPPPYSRYPMD
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 269 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | YAP WW1 | 1 |
| 2 | Smad7 derived peptide | 2 |
Entities:
Entity 1, YAP WW1 36 residues - 4151.635 Da.
| 1 | ASP | VAL | PRO | LEU | PRO | ALA | GLY | TRP | GLU | MET | ||||
| 2 | ALA | LYS | THR | SER | SER | GLY | GLN | ARG | TYR | PHE | ||||
| 3 | LEU | ASN | HIS | ILE | ASP | GLN | THR | THR | THR | TRP | ||||
| 4 | GLN | ASP | PRO | ARG | LYS | ALA |
Entity 2, Smad7 derived peptide 14 residues - 1593.747 Da.
| 1 | GLY | GLU | SER | PRO | PRO | PRO | PRO | TYR | SER | ARG | ||||
| 2 | TYR | PRO | MET | ASP |