BMRB Entry 18757

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PDB ID: 2lzi
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR18757
MolProbity Validation Chart

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Title:
High resolution NMR structure of the theta-defensin HTD-2 (retrocyclin 2)
Deposition date:
2012-10-02
Original release date:
2012-11-27
Authors:
Conibear, Anne; Rosengren, K. Johan; Harvey, Peta; Craik, David
Citation:

Citation: Conibear, Anne; Rosengren, K. Johan; Harvey, Peta; Craik, David. "Structural Characterization of the Cyclic Cystine Ladder Motif of -Defensins."  Biochemistry 51, 9718-9726 (2012).
PubMed: 23148585

Assembly members:

Assembly members:
HTD-2, polymer, 18 residues, 2046.613 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
HTD-2: GICRCICGRRICRCICGR

Data sets:
Data typeCount
13C chemical shifts49
15N chemical shifts10
1H chemical shifts117

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1theta-defensin HTD-2 (retrocyclin 2)1

Entities:

Entity 1, theta-defensin HTD-2 (retrocyclin 2) 18 residues - 2046.613 Da.

This is a head-to-tail cyclic peptide with a peptide bond between Arg18 and Gly1.

1   GLYILECYSARGCYSILECYSGLYARGARG
2   ILECYSARGCYSILECYSGLYARG

Related Database Links:

GB AF355799
PDB 2LZI

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