BMRB Entry 18763
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PDB ID: 2lzl
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR18763
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry
Citation: Bocharov, Eduard; Lesovoy, Dmitry; Goncharuk, Sergey; Goncharuk, Marina; Hristova, Kalina; Arseniev, Alexander. "Structure of FGFR3 transmembrane domain dimer: implications for signaling and human pathologies." Structure 21, 2087-2093 (2013).
PubMed: 24120763
Assembly members:
FGFR3tm, polymer, 43 residues, 4604.369 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pGEMEX-1/(TRX-tmFGFR3)
Entity Sequences (FASTA):
FGFR3tm: LPAEEELVEADEAGSVYAGI
LSYGVGFFLFILVVAAVTLC
RLR
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 189 |
| 15N chemical shifts | 47 |
| 1H chemical shifts | 322 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | FGFR3tm_1 | 1 |
| 2 | FGFR3tm_2 | 1 |
Entities:
Entity 1, FGFR3tm_1 43 residues - 4604.369 Da.
| 1 | LEU | PRO | ALA | GLU | GLU | GLU | LEU | VAL | GLU | ALA | ||||
| 2 | ASP | GLU | ALA | GLY | SER | VAL | TYR | ALA | GLY | ILE | ||||
| 3 | LEU | SER | TYR | GLY | VAL | GLY | PHE | PHE | LEU | PHE | ||||
| 4 | ILE | LEU | VAL | VAL | ALA | ALA | VAL | THR | LEU | CYS | ||||
| 5 | ARG | LEU | ARG |
Related Database Links:
| PDB | 2LZL |
| DBJ | BAD92678 BAI45440 BAI45449 |
| GB | AAA52450 AAA58470 AAB33323 AAI21176 AAI28611 |
| REF | NP_000133 NP_001156685 XP_001101108 XP_002802213 XP_003310269 |
| SP | P22607 |
| AlphaFold | P22607 |
Download HSQC peak lists in one of the following formats:
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SPARKY: Backbone
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