BMRB Entry 19379

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PDB ID: 2maw
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR19379
MolProbity Validation Chart

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Title:
NMR structures of the alpha7 nAChR transmembrane domain.
Deposition date:
2013-07-19
Original release date:
2013-11-11
Authors:
Bondarenko, Vasyl; Mowrey, David; Xu, Yan; Tang, Pei
Citation:

Citation: Bondarenko, Vasyl; Mowrey, David; Tillman, Tommy; Seyoum, Edom; Xu, Yan; Tang, Pei. "NMR structures of the human 7 nAChR transmembrane domain and associated anesthetic binding sites."  Biochim. Biophys. Acta ., .-. (2013).
PubMed: 24384062

Assembly members:

Assembly members:
entity, polymer, 137 residues, 14309.850 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pTBSG

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity: SNAEEELYYGLNLLIPCVLI SALALLVFLLPADSGEKISL GITVLLSLTVFMLLVAEIMP STSDSSPSIAQYFASTMIIV GLSVVVTVIVLQYHHHDPDG GEGGGEGIDRLCLMAFSVFT IICTIGILMSAPNFVEE

Data sets:
Data typeCount
13C chemical shifts473
15N chemical shifts128
1H chemical shifts712

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1alpha7 nAChR transmembrane domain1

Entities:

Entity 1, alpha7 nAChR transmembrane domain 137 residues - 14309.850 Da.

1   SERASNALAGLUGLUGLULEUTYRTYRGLY
2   LEUASNLEULEUILEPROCYSVALLEUILE
3   SERALALEUALALEULEUVALPHELEULEU
4   PROALAASPSERGLYGLULYSILESERLEU
5   GLYILETHRVALLEULEUSERLEUTHRVAL
6   PHEMETLEULEUVALALAGLUILEMETPRO
7   SERTHRSERASPSERSERPROSERILEALA
8   GLNTYRPHEALASERTHRMETILEILEVAL
9   GLYLEUSERVALVALVALTHRVALILEVAL
10   LEUGLNTYRHISHISHISASPPROASPGLY
11   GLYGLUGLYGLYGLYGLUGLYILEASPARG
12   LEUCYSLEUMETALAPHESERVALPHETHR
13   ILEILECYSTHRILEGLYILELEUMETSER
14   ALAPROASNPHEVALGLUGLU

Related Database Links:

PDB 2MAW

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