BMRB Entry 19953
Click here to enlarge.
PDB ID: 2mov
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full
BMRB Entry DOI: doi:10.13018/BMR19953
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry
Citation: Xue, Jing; Ray, Rasmi; Singer, David; Bohme, David; Burz, David; Rai, Vivek; Hoffman, Ralf; Shekhtman, Alexander. "The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs" Biochemistry 53, 3327-3335 (2014).
PubMed: 24824951
Assembly members:
V_domain, polymer, 105 residues, 11571.429 Da.
N~5~-[(2S,4S,5R)-4-hydroxy-5-methylimidazolidin-2-yl]-L-ornithine, non-polymer, 232.280 Da.
Natural source: Common Name: human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET28-V
Entity Sequences (FASTA):
V_domain: GSAQNITARIGEPLVLKCKG
APKKPPQRLEWKLNTGRTEA
WKVLSPQGGGPWDSVARVLP
NGSLFLPAVGIQDEGIFRCQ
AMNRNGKETKSNYRVRVYQI
PGKPE
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 623 |
| 13C chemical shifts | 345 |
| 15N chemical shifts | 92 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | V_domain | 1 |
| 2 | IOR | 2 |
Entities:
Entity 1, V_domain 105 residues - 11571.429 Da.
Residues 1-3 represent a non-native affinity tag.
| 1 | GLY | SER | ALA | GLN | ASN | ILE | THR | ALA | ARG | ILE | ||||
| 2 | GLY | GLU | PRO | LEU | VAL | LEU | LYS | CYS | LYS | GLY | ||||
| 3 | ALA | PRO | LYS | LYS | PRO | PRO | GLN | ARG | LEU | GLU | ||||
| 4 | TRP | LYS | LEU | ASN | THR | GLY | ARG | THR | GLU | ALA | ||||
| 5 | TRP | LYS | VAL | LEU | SER | PRO | GLN | GLY | GLY | GLY | ||||
| 6 | PRO | TRP | ASP | SER | VAL | ALA | ARG | VAL | LEU | PRO | ||||
| 7 | ASN | GLY | SER | LEU | PHE | LEU | PRO | ALA | VAL | GLY | ||||
| 8 | ILE | GLN | ASP | GLU | GLY | ILE | PHE | ARG | CYS | GLN | ||||
| 9 | ALA | MET | ASN | ARG | ASN | GLY | LYS | GLU | THR | LYS | ||||
| 10 | SER | ASN | TYR | ARG | VAL | ARG | VAL | TYR | GLN | ILE | ||||
| 11 | PRO | GLY | LYS | PRO | GLU |
Entity 2, IOR - 232.280 Da.
| 1 | IOR |
Related Database Links:
| REF | NP_001127 NP_001127 NP_001192046 NP_001193858 NP_001193863 NP_001193865 |
| BMRB | 17378 19739 |
| PDB | 2E5E 2L7U 2M1K 2MJW 2MOV 3CJJ 3O3U 4LP4 4LP5 4OF5 4OFV 4OI7 4OI8 4P2Y |
| DBJ | BAA05958 BAA89369 BAC65465 BAG35995 BAG60385 |
| GB | AAA03574 AAB47491 AAH20669 AAX07272 AAX07273 |
| SP | Q15109 |
| AlphaFold | Q15109 |
Download HSQC peak lists in one of the following formats:
CSV: Backbone
or all simulated peaks
SPARKY: Backbone
or all simulated peaks