BMRB Entry 19989

Title:
Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: the N-terminal Region of CCR3 Bound to CCL11/Eotaxin-1
Deposition date:
2014-05-26
Original release date:
2014-12-08
Authors:
Millard, Christopher; Ludeman, Justin; Canals, Meritxell; Bridgford, Jessica; Hinds, Mark; Clayton, Daniel; Christopoulos, Arthur; Payne, Richard; Stone, Martin
Citation:

Citation: Millard, Christopher; Ludeman, Justin; Canals, Meritxell; Bridgford, Jessica; Hinds, Mark; Clayton, Daniel; Christopoulos, Arthur; Payne, Richard; Stone, Martin. "Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: The N-Terminal Region of CCR3 Bound to CCL11/Eotaxin-1"  Structure 22, 1571-1581 (2014).
PubMed: 25450766

Assembly members:

Assembly members:
entity_1, polymer, 74 residues, 8381.003 Da.
entity_2, polymer, 16 residues, 1940.029 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET-28a

Entity Sequences (FASTA):

Data sets:
Data typeCount
1H chemical shifts576
13C chemical shifts225
15N chemical shifts74

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1entity_11
2entity_22

Entities:

Entity 1, entity_1 74 residues - 8381.003 Da.

1   GLYPROALASERVALPROTHRTHRCYSCYS
2   PHEASNLEUALAASNARGLYSILEPROLEU
3   GLNARGLEUGLUSERTYRARGARGILETHR
4   SERGLYLYSCYSPROGLNLYSALAVALILE
5   PHELYSTHRLYSLEUALALYSASPILECYS
6   ALAASPPROLYSLYSLYSTRPVALGLNASP
7   SERMETLYSTYRLEUASPGLNLYSSERPRO
8   THRPROLYSPRO

Entity 2, entity_2 16 residues - 1940.029 Da.

1   VALGLUTHRPHEGLYTHRTHRSERTYSTYS
2   ASPASPVALGLYLEULEU

Related Database Links:

BMRB 4155 4390
PDB 1EOT 2EOT 2MPM
DBJ BAA08370 BAG72995
EMBL CAA99997 CAA99998 CAB07027 CAG33702
GB AAA98957 AAC50369 AAC51297 AAH17850 ABK41951
PRF 2208449A
REF NP_002977 XP_002827294 XP_003818054 XP_004041989 XP_004041990
SP P51671
AlphaFold P51671

Download HSQC peak lists in one of the following formats:
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