BMRB Entry 25818

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PDB ID: 2n7r
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR25818
MolProbity Validation Chart

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Title:
Structure of the transmembrane domain of human nicastrin in DPC micelles
Deposition date:
2015-09-17
Original release date:
2016-04-25
Authors:
Li, Yan; Liew, Lynette; Li, Qingxin; Kang, CongBao
Citation:

Citation: Li, Yan; Liew, Lynette; Li, Qingxin; Kang, CongBao. "Structure of the transmembrane domain of human nicastrin-a component of -secretase"  Sci. Rep. 6, 19522-19522 (2016).
PubMed: 26776682

Assembly members:

Assembly members:
transmembrane_domain_of_human_nicastrin, polymer, 54 residues, 4960.896 Da.

Natural source:

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET29b

Entity Sequences (FASTA):

Entity Sequences (FASTA):
transmembrane_domain_of_human_nicastrin: MAHHHHHHASKELELITLTV GFGILIFSLIVTYCINAKAD VLFIAPREPGAVSY

Data sets:
Data typeCount
13C chemical shifts120
15N chemical shifts45
1H chemical shifts254

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1transmembrane_domain_of_human_nicastrin1

Entities:

Entity 1, transmembrane_domain_of_human_nicastrin 54 residues - 4960.896 Da.

1   METALAHISHISHISHISHISHISALASER
2   LYSGLULEUGLULEUILETHRLEUTHRVAL
3   GLYPHEGLYILELEUILEPHESERLEUILE
4   VALTHRTYRCYSILEASNALALYSALAASP
5   VALLEUPHEILEALAPROARGGLUPROGLY
6   ALAVALSERTYR

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