BMRB Entry 30517

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PDB ID: 6mie
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR30517
MolProbity Validation Chart

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Title:
Solution NMR structure of the KCNQ1 voltage-sensing domain
Deposition date:
2018-09-19
Original release date:
2020-02-28
Authors:
Taylor, K.; Kuenze, G.; Smith, J.; Meiler, J.; McFeeters, R.; Sanders, C.
Citation:

Citation: Taylor, K.; Kang, P.; Hou, P.; Kuenze, G.; Yang, N.; Smith, J.; Shi, J.; Huang, H.; White, K.; Peng, D.; George, A.; Meiler, J.; McFeeters, R.; Cui, J.; Sanders, C.. "Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state"  Elife 9, e53901-e53901 (2020).
PubMed: 32096762

Assembly members:

Assembly members:
entity_1, polymer, 159 residues, 18184.631 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET16b

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: MGHHHHHHGVLARTHVQGRV YNFLERPTGWKCFVYHFAVF LIVLVCLIFSVLSTIEQYAA LATGTLFWMEIVLVVFFGTE YVVRLWSAGCRSKYVGLWGR LRFARKPISIIDLIVVVASM VVLCVGSKGQVFATSAIRGI RFLQILRMLHVDRQGGTWR

Data sets:
Data typeCount
13C chemical shifts506
15N chemical shifts145
1H chemical shifts926

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1entity_11

Entities:

Entity 1, entity_1 159 residues - 18184.631 Da.

1   METGLYHISHISHISHISHISHISGLYVAL
2   LEUALAARGTHRHISVALGLNGLYARGVAL
3   TYRASNPHELEUGLUARGPROTHRGLYTRP
4   LYSCYSPHEVALTYRHISPHEALAVALPHE
5   LEUILEVALLEUVALCYSLEUILEPHESER
6   VALLEUSERTHRILEGLUGLNTYRALAALA
7   LEUALATHRGLYTHRLEUPHETRPMETGLU
8   ILEVALLEUVALVALPHEPHEGLYTHRGLU
9   TYRVALVALARGLEUTRPSERALAGLYCYS
10   ARGSERLYSTYRVALGLYLEUTRPGLYARG
11   LEUARGPHEALAARGLYSPROILESERILE
12   ILEASPLEUILEVALVALVALALASERMET
13   VALVALLEUCYSVALGLYSERLYSGLYGLN
14   VALPHEALATHRSERALAILEARGGLYILE
15   ARGPHELEUGLNILELEUARGMETLEUHIS
16   VALASPARGGLNGLYGLYTHRTRPARG

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