BMRB Entry 30695

Title:
Solution structure of delta-theraphotoxin-Hm1b from Heteroscodra maculata
Deposition date:
2019-12-05
Original release date:
2020-05-08
Authors:
Chin, Y.; Chow, C.; King, G.
Citation:

Citation: Chow, C.; Chin, Y.; Ma, L.; Undheim, E.; Herzig, V.; King, G.. "A selective NaV1.1 activator with potential for treatment of Dravet syndrome epilepsy"  Biochem. Pharmacol. ., 113991-113991 (2020).
PubMed: 32335140

Assembly members:

Assembly members:
entity_1, polymer, 35 residues, 3993.551 Da.

Natural source:

Natural source:   Common Name: Togo starburst tarantula   Taxonomy ID: 268413   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Heteroscodra maculata

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: SECRYLFGGCKTTADCCKHL GCRTDLYYCAWDGTF

Data sets:
Data typeCount
13C chemical shifts106
15N chemical shifts37
1H chemical shifts219

Additional metadata:

  • Assembly
  • Samples and Experiments
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  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1entity_11

Entities:

Entity 1, entity_1 35 residues - 3993.551 Da.

1   SERGLUCYSARGTYRLEUPHEGLYGLYCYS
2   LYSTHRTHRALAASPCYSCYSLYSHISLEU
3   GLYCYSARGTHRASPLEUTYRTYRCYSALA
4   TRPASPGLYTHRPHE

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks