BMRB Entry 51928

Title:
Solid-state NMR data for 40-residue Arctic (E22G) Beta-Amyloid Fibril
Deposition date:
2023-04-18
Original release date:
2024-09-27
Authors:
Tehrani, Mohammad; Isamu, Matsuda; Matsunaga, Tatsuya; Ishii, Yoshitaka
Citation:

Citation: Tehrani, Mohammad Jafar; Matsuda, Isamu; Yamagata, Atsushi; Kodama, Yu; Matsunaga, Tatsuya; Sato, Mayuko; Toyooka, Kiminori; McElheny, Dan; Kobayashi, Naohiro; Shirouzu, Mikako; Ishii, Yoshitaka. "E22G Ab40 fibril structure and kinetics illuminate how Ab40 rather than Ab42 triggers familial Alzheimer's"  Nat. Commun. 15, 7045-7045 (2024).
PubMed: 39147751

Assembly members:

Assembly members:
entity_1, polymer, 40 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: DAEFRHDSGYEVHHQKLVFF AGDVGSNKGAIIGLMVGGVV

Data sets:
Data typeCount
13C chemical shifts95

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1E22G Abeta401

Entities:

Entity 1, E22G Abeta40 40 residues - Formula weight is not available

1   ASPALAGLUPHEARGHISASPSERGLYTYR
2   GLUVALHISHISGLNLYSLEUVALPHEPHE
3   ALAGLYASPVALGLYSERASNLYSGLYALA
4   ILEILEGLYLEUMETVALGLYGLYVALVAL