BMRB Entry 52458

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR52458

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Title:
FOXO4-LRI chemical shifts bound to p53TAD2
Deposition date:
2024-05-13
Original release date:
2025-01-31
Authors:
Bourgeois, Benjamin; Spreitzer, Emil; Platero-Rochart, Daniel; Zhou, Qishun; Usluer, Sinem; de Keizer, Peter; Burgering, Boudewijn; Sanchez-Murcia, Pedro; Madl, Tobias
Citation:

Citation: Bourgeois, Benjamin; Spreitzer, Emil; Platero-Rochart, Daniel; Zhou, Qishun; Usluer, Sinem; de Keizer, Peter; Burgering, Boudewijn; Sanchez-Murcia, Pedro; Madl, Tobias. "The Disordered p53 Transactivation Domain is the Target of FOXO4 and the Senolytic Compound FOXO4-DRI"  Nat. Commun. ., .-..

Assembly members:

Assembly members:
entity_1, polymer, 46 residues, Formula weight is not available
entity_2, polymer, 21 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pETM11-ZZ-His6

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: LTLRKEPASEIAQSILEAYS QNGWANRRSGGKRPPPRRRQ RRKKRG
entity_2: SQAMDDLMLSPDDIEQWFTE D

Data sets:
Data typeCount
13C chemical shifts100
15N chemical shifts29
1H chemical shifts195

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1FOXO4-LRI1
2p53TAD22

Entities:

Entity 1, FOXO4-LRI 46 residues - Formula weight is not available

1   LEUTHRLEUARGLYSGLUPROALASERGLU
2   ILEALAGLNSERILELEUGLUALATYRSER
3   GLNASNGLYTRPALAASNARGARGSERGLY
4   GLYLYSARGPROPROPROARGARGARGGLN
5   ARGARGLYSLYSARGGLY

Entity 2, p53TAD2 21 residues - Formula weight is not available

1   SERGLNALAMETASPASPLEUMETLEUSER
2   PROASPASPILEGLUGLNTRPPHETHRGLU
3   ASP

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