BMRB Entry 16420

Title:
Protein stablilization by specific binding of guanidinium to a functional arginine-binding surface on an SH3 domain
Deposition date:
2009-07-23
Original release date:
2015-09-18
Authors:
Zarrine-Afsar, Arash; Mittermaier, Anthony; Kay, Lewis; Davidson, Alan
Citation:

Citation: Zarrine-Afsar, Arash; Mittermaier, Anthony; Kay, Lewis; Davidson, Alan. "Protein stabilization by specific binding of guanidinium to a functional arginine-binding surface on an SH3 domain"  Protein Sci. 1, 162-170 (2006).
PubMed: 16373478

Assembly members:

Assembly members:
Fyn_SH3_domain, polymer, 59 residues, 6733.33 Da.
GuHCl, non-polymer, 59.070 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: n/a

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Fyn_SH3_domain: VTLFVALYDYEARTEDDLSF HKGEKFQILNSSEGDWWEAR SLTTGETGYIPSNYVAPVD

Data sets:
Data typeCount

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1Fyn SH3 domain1
2Guanidium chloride2

Entities:

Entity 1, Fyn SH3 domain 59 residues - 6733.33 Da.

1   VALTHRLEUPHEVALALALEUTYRASPTYR
2   GLUALAARGTHRGLUASPASPLEUSERPHE
3   HISLYSGLYGLULYSPHEGLNILELEUASN
4   SERSERGLUGLYASPTRPTRPGLUALAARG
5   SERLEUTHRTHRGLYGLUTHRGLYTYRILE
6   PROSERASNTYRVALALAPROVALASP

Entity 2, Guanidium chloride - . - 59.070 Da.

1   .

Related Database Links:

PDB 1shf 1A0N 1AVZ 1AZG 1EFN 1FYN 1G83 1M27 1NYF 1NYG 1SHF 1ZBJ 3H0F 3H0H 3H0I 3UA6 3UA7 3UF4 4D8D 4EIK
DBJ BAE33766 BAE42585 BAG70107 BAG70240 BAI46902
EMBL CAA37025 CAC44028
GB AAA36615 AAA37644 AAA82942 AAB09568 AAB33113
REF NP_001071440 NP_001073675 NP_001116364 NP_001116365 NP_002028
SP A0JNB0 A1Y2K1 P06241 P39688 Q05876
TPG DAA26259
AlphaFold A0JNB0 A1Y2K1 P06241 P39688 Q05876