BMRB Entry 16776

Title:
C-terminal domain of mesencephalic astrocyte-derived neurotrophic factor (MANF)
Deposition date:
2010-03-12
Original release date:
2022-02-14
Authors:
Hellman, Maarit; Saarma, Mart; Permi, Perttu
Citation:

Citation: Hellman, Maarit; Arumae, Urmas; Yu, Li-ying; Lindholm, Paivi; Peranen, Johan; Saarma, Mart; Permi, Perttu. "Mesencephalic astrocyte-derived neurotrophic factor (MANF) has a unique mechanism to rescue apoptotic neurons"  J. Biol. Chem. 286, 2675-2680 (2011).
PubMed: 21047780

Assembly members:

Assembly members:
C-MANF, polymer, 65 residues, 7476.837 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET15b

Entity Sequences (FASTA):

Data sets:
Data typeCount
13C chemical shifts227
15N chemical shifts61
1H chemical shifts461

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1C-MANF1

Entities:

Entity 1, C-MANF 65 residues - 7476.837 Da.

First two residues are cloning artefacts

1   METGLYLYSTYRASPLYSGLNILEASPLEU
2   SERTHRVALASPLEULYSLYSLEUARGVAL
3   LYSGLULEULYSLYSILELEUASPASPTRP
4   GLYGLUTHRCYSLYSGLYCYSALAGLULYS
5   SERASPTYRILEARGLYSILEASNGLULEU
6   METPROLYSTYRALAPROLYSALAALASER
7   ALAARGTHRASPLEU

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SPARKY: Backbone or all simulated peaks