BMRB Entry 18748

Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR18748

NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry

Title:
Backbone chemical shift assignments of the C-terminal SH3 domain of Grb2
Deposition date:
2012-10-01
Original release date:
2012-11-02
Authors:
Ghosh, Ragini; Ladbury, John
Citation:

Citation: Ghosh, Ragini; Ladbury, John. "Inhibition of Basal FGF Receptor Signaling by Dimeric Grb2"  Cell 149, 1514-1524 (2012).
PubMed: 22726438

Assembly members:

Assembly members:
Grb2_C-terminal_SH3_domain, polymer, 74 residues, 8599 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pQE30

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Grb2_C-terminal_SH3_domain: MRGSHHHHHHGSQQPTYVQA LFDFDPQEDGELGFRRGDFI HVMDNSDPNWWKGACHGQTG MFPRNYVTPVNRNV

Data sets:
Data typeCount
13C chemical shifts158
15N chemical shifts50
1H chemical shifts50

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Grb2 C-terminal SH3 domain1

Entities:

Entity 1, Grb2 C-terminal SH3 domain 74 residues - 8599 Da.

1   METARGGLYSERHISHISHISHISHISHIS
2   GLYSERGLNGLNPROTHRTYRVALGLNALA
3   LEUPHEASPPHEASPPROGLNGLUASPGLY
4   GLULEUGLYPHEARGARGGLYASPPHEILE
5   HISVALMETASPASNSERASPPROASNTRP
6   TRPLYSGLYALACYSHISGLYGLNTHRGLY
7   METPHEPROARGASNTYRVALTHRPROVAL
8   ASNARGASNVAL

Related Database Links:

PDB 1GCQ 1GFC 1GFD 1IO6 2VVK 2VWF 2W0Z
EMBL CAA44664
GB ELK30972 ELW68317 ERE69131
REF XP_006728173 XP_006940642 XP_008766679 XP_010340838 XP_010629093

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks