BMRB Entry 27339

Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR27339

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Title:
Chemical shifts of UBQLN2 residues 450-624
Deposition date:
2017-12-11
Original release date:
2018-03-16
Authors:
Castaneda, Carlos
Citation:

Citation: Dao, Thuy; Kolaitis, Regina-Maria; Kim, Hong Joo; O'Donovan, Kevin; Martyniak, Brian; Colicino, Erica; Hehnly, Heidi; Taylor, J Paul; Castaneda, Carlos. "Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions"  Mol. Cell S1097, 30102-30103 (2018).
PubMed: 29526694

Assembly members:

Assembly members:
UBQLN2_450-624, polymer, 177 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET24b

Entity Sequences (FASTA):

Entity Sequences (FASTA):
UBQLN2_450-624: MRAMQALMQIQQGLQTLATE APGLIPSFTPGVGVGVLGTA IGPVGPVTPIGPIGPIVPFT PIGPIGPIGPTGPAAPPGST GSGGPTGPTVSSAAPSETTS PTSESGPNQQFIQQMVQALA GANAPQLPNPEVRFQQQLEQ LNAMGFLNREANLQALIATG GDINAAIERLLGSQPSW

Data sets:
Data typeCount
13C chemical shifts435
15N chemical shifts147
1H chemical shifts132

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1UBQLN21

Entities:

Entity 1, UBQLN2 177 residues - Formula weight is not available

Second residue R is residue 450 of human UBQLN2. Additional C-terminal residue W for prot concentration measurements.

1   METARGALAMETGLNALALEUMETGLNILE
2   GLNGLNGLYLEUGLNTHRLEUALATHRGLU
3   ALAPROGLYLEUILEPROSERPHETHRPRO
4   GLYVALGLYVALGLYVALLEUGLYTHRALA
5   ILEGLYPROVALGLYPROVALTHRPROILE
6   GLYPROILEGLYPROILEVALPROPHETHR
7   PROILEGLYPROILEGLYPROILEGLYPRO
8   THRGLYPROALAALAPROPROGLYSERTHR
9   GLYSERGLYGLYPROTHRGLYPROTHRVAL
10   SERSERALAALAPROSERGLUTHRTHRSER
11   PROTHRSERGLUSERGLYPROASNGLNGLN
12   PHEILEGLNGLNMETVALGLNALALEUALA
13   GLYALAASNALAPROGLNLEUPROASNPRO
14   GLUVALARGPHEGLNGLNGLNLEUGLUGLN
15   LEUASNALAMETGLYPHELEUASNARGGLU
16   ALAASNLEUGLNALALEUILEALATHRGLY
17   GLYASPILEASNALAALAILEGLUARGLEU
18   LEUGLYSERGLNPROSERTRP

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