BMRB Entry 28070

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR28070

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Title:
Backbone resonances of the cSH2 domain of SHP2
Deposition date:
2020-02-09
Original release date:
2020-11-13
Authors:
Marasco, Michelangelo; Kirkpatrick, John; Carlomagno, Teresa
Citation:

Citation: Marasco, Michelangelo; Kirkpatrick, John; Carlomagno, Teresa. "1H, 13C, 15N chemical shift assignments of SHP2 SH2 domains in complex with PD-1 immune-tyrosine motifs"  Biomol. NMR Assign. 14, 179-188 (2020).
PubMed: 32236803

Assembly members:

Assembly members:
cSH2, polymer, 119 residues, 13283.9213 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pETM22

Entity Sequences (FASTA):

Entity Sequences (FASTA):
cSH2: GPMADPTSERWFHGHLSGKE AEKLLTEKGKHGSFLVRESQ SHPGDFVLSVRTGDDKGESN DGKSKVTHVMIRCQELKYDV GGGERFDSLTDLVEHYKKNP MVETLGTVLQLKQPLNTTR

Data sets:
Data typeCount
13C chemical shifts222
15N chemical shifts110
1H chemical shifts110

Additional metadata:

  • Assembly
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Assembly:

Entity Assembly IDEntity NameEntity ID
1cSH21

Entities:

Entity 1, cSH2 119 residues - 13283.9213 Da.

1   GLYPROMETALAASPPROTHRSERGLUARG
2   TRPPHEHISGLYHISLEUSERGLYLYSGLU
3   ALAGLULYSLEULEUTHRGLULYSGLYLYS
4   HISGLYSERPHELEUVALARGGLUSERGLN
5   SERHISPROGLYASPPHEVALLEUSERVAL
6   ARGTHRGLYASPASPLYSGLYGLUSERASN
7   ASPGLYLYSSERLYSVALTHRHISVALMET
8   ILEARGCYSGLNGLULEULYSTYRASPVAL
9   GLYGLYGLYGLUARGPHEASPSERLEUTHR
10   ASPLEUVALGLUHISTYRLYSLYSASNPRO
11   METVALGLUTHRLEUGLYTHRVALLEUGLN
12   LEULYSGLNPROLEUASNTHRTHRARG

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks