BMRB Entry 28117

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR28117

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Title:
Heterogeneous ribonucleoprotein A18 RNA Recognition Motif
Deposition date:
2020-04-27
Original release date:
2021-02-13
Authors:
Roth, Braden; Coburn, Katherine; Weber, David; Varney, Kristen
Citation:

Citation: Solano-Gonzalez, Eduardo; Yu, Wenbo; Coburn, Katherine; Wilson, Gerald; Nurmemmedov, Elmar; Kesari, Santosh; Chang, Elizabeth; MacKerell, Alexander; Weber, David; Carrier, France. "Small molecules inhibitors of the heterogeneous ribonuclear protein A18 (hnRNP A18): a regulator of protein translation and an immune checkpoint"  Nucleic Acids Res. 49, 1235-1246 (2021).
PubMed: 33398344

Assembly members:

Assembly members:
A18n, polymer, 93 residues, 10213.2362 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: N/A

Entity Sequences (FASTA):

Entity Sequences (FASTA):
A18n: GMASDEGKLFVGGLSFDTNE QSLEQVFSKYGQISEVVVVK DRETQRSRGFGFVTFENIDD AKDAMMAMNGKSVDGRQIRV DQAGKSSDNRSRG

Data sets:
Data typeCount
13C chemical shifts350
15N chemical shifts91
1H chemical shifts552

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1A18n1

Entities:

Entity 1, A18n 93 residues - 10213.2362 Da.

1   GLYMETALASERASPGLUGLYLYSLEUPHE
2   VALGLYGLYLEUSERPHEASPTHRASNGLU
3   GLNSERLEUGLUGLNVALPHESERLYSTYR
4   GLYGLNILESERGLUVALVALVALVALLYS
5   ASPARGGLUTHRGLNARGSERARGGLYPHE
6   GLYPHEVALTHRPHEGLUASNILEASPASP
7   ALALYSASPALAMETMETALAMETASNGLY
8   LYSSERVALASPGLYARGGLNILEARGVAL
9   ASPGLNALAGLYLYSSERSERASPASNARG
10   SERARGGLY

Related Database Links:

PDB 5TBX

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