BMRB Entry 30811

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PDB ID: 7knn
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR30811
MolProbity Validation Chart

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Title:
Solution structure of the alpha-conotoxin analogue [2-8]-alkyne Vc1.1
Deposition date:
2020-11-05
Original release date:
2021-09-07
Authors:
MacRaild, C.; Robinson, S.; Chhabra, S.; Norton, R.
Citation:

Citation: Belgi, Alessia; Burnley, James; MacRaild, Christopher; Chhabra, Sandeep; Elnahriry, Khaled; Robinson, Samuel; Gooding, Simon; Tae, Han-Shen; Bartels, Peter; Sadeghi, Mahsa; Zhao, Fei-Yue; Wei, Haifeng; Spanswick, David; Adams, David; Norton, Raymond; Robinson, Andrea. "Alkyne-Bridged alpha-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models"  J. Med. Chem. 64, 3222-3233 (2021).
PubMed: 33724033

Assembly members:

Assembly members:
entity_1, polymer, 16 residues, 1777.934 Da.

Natural source:

Natural source:   Common Name: Queen Victoria cone   Taxonomy ID: 319920   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Conus victoriae

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: GXCSDPRXNYDHPEIC

Data sets:
Data typeCount
13C chemical shifts46
15N chemical shifts14
1H chemical shifts85

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1unit_11

Entities:

Entity 1, unit_1 16 residues - 1777.934 Da.

1   GLYABACYSSERASPPROARGABAASNTYR
2   ASPHISPROGLUILECYS

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