BMRB Entry 31066

Click here to enlarge.

PDB ID: 8flp
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR31066
MolProbity Validation Chart

NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry

Title:
NMR Solution Structure of LvIC analogue
Deposition date:
2022-12-22
Original release date:
2023-01-31
Authors:
Harvey, P.; Craik, D.
Citation:

Citation: Zhu, X.; Wang, S.; Kaas, Q.; Yu, J.; Wu, Y.; Harvey, P.; Zhangsun, D.; Craik, D.; Luo, S.. "Discovery, Characterization and Engineering of LvIC, an alpha 4/4-Conotoxin That Selectively Blocks Rat alpha6/alpha3beta4 Nicotinic Acetylcholine Receptors"  J. Med. Chem. 66, 2020-2031 (2023).
PubMed: 36682014

Assembly members:

Assembly members:
entity_1, polymer, 14 residues, 1305.553 Da.

Natural source:

Natural source:   Common Name: Conus lividus   Taxonomy ID: 89426   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Conus lividus

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: GCCANPVCNGKHCX

Data sets:
Data typeCount
13C chemical shifts30
1H chemical shifts69

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1unit_11

Entities:

Entity 1, unit_1 14 residues - 1305.553 Da.

1   GLYCYSCYSALAASNPROVALCYSASNGLY
2   LYSHISCYSNH2