BMRB Entry 31122

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PDB ID: 8urv
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR31122
MolProbity Validation Chart

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Title:
Solution NMR structure of pro-IL-18
Deposition date:
2023-10-26
Original release date:
2024-05-21
Authors:
Bonin, J.; Aramini, J.; Kay, L.
Citation:

Citation: Dong, Ying; Bonin, Jeffrey; Devant, Pascal; Liang, Zhuoyi; Sever, Alexander; Mintseris, Julian; Aramini, James; Du, Gang; Gygi, Stephen; Kagan, Jonathan; Kay, Lewis; Wu, Hao. "Structural transitions enable interleukin-18 maturation and signaling"  Immunity 57, 1533-1548 (2024).
PubMed: 38733997

Assembly members:

Assembly members:
entity_1, polymer, 193 residues, 22350.225 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: MAAEPVEDNCINFVAMKFID NTLYFIAEDDENLESDYFGK LESKLSVIRNLNDQVLFIDQ GNRPLFEDMTDSDCRDNAPR TIFIISMYKDSQPRGMAVTI SVKCEKISTLSCENKIISFK EMNPPDNIKDTKSDIIFFQR SVPGHDNKMQFESSSYEGYF LACEKERDLFKLILKKEDEL GDRSIMFTVQNED

Data sets:
Data typeCount
13C chemical shifts901
15N chemical shifts203
1H chemical shifts1380

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1unit_11

Entities:

Entity 1, unit_1 193 residues - 22350.225 Da.

1   METALAALAGLUPROVALGLUASPASNCYS
2   ILEASNPHEVALALAMETLYSPHEILEASP
3   ASNTHRLEUTYRPHEILEALAGLUASPASP
4   GLUASNLEUGLUSERASPTYRPHEGLYLYS
5   LEUGLUSERLYSLEUSERVALILEARGASN
6   LEUASNASPGLNVALLEUPHEILEASPGLN
7   GLYASNARGPROLEUPHEGLUASPMETTHR
8   ASPSERASPCYSARGASPASNALAPROARG
9   THRILEPHEILEILESERMETTYRLYSASP
10   SERGLNPROARGGLYMETALAVALTHRILE
11   SERVALLYSCYSGLULYSILESERTHRLEU
12   SERCYSGLUASNLYSILEILESERPHELYS
13   GLUMETASNPROPROASPASNILELYSASP
14   THRLYSSERASPILEILEPHEPHEGLNARG
15   SERVALPROGLYHISASPASNLYSMETGLN
16   PHEGLUSERSERSERTYRGLUGLYTYRPHE
17   LEUALACYSGLULYSGLUARGASPLEUPHE
18   LYSLEUILELEULYSLYSGLUASPGLULEU
19   GLYASPARGSERILEMETPHETHRVALGLN
20   ASNGLUASP

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