BMRB Entry 34070
Click here to enlarge.
PDB ID: 5mhd
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR34070
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry
Citation: Bednarek, E.; Sitkowski, J.; Bocian, W.; Borowicz, P.; Pucienniczak, G.; Stadnik, D.; Surmacz-Chwedoruk, W.; Jaworska, B.; Kozerski, L.. "Structure and pharmaceutical formulation development of a new long-acting recombinant human insulin analog studied by NMR and MS." J. Pharm. Biomed. Anal. 135, 126-132 (2017).
PubMed: 28024260
Assembly members:
Insulin, polymer, 22 residues, 2470.776 Da.
Insulin, polymer, 31 residues, 3606.224 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
Insulin: GIVEQCCTSICSLYQLENYC
NS
Insulin: FVKQHLCGSHLVEALYLVCG
ERGFFYTPKTR
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 351 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | entity_1 | 1 |
| 2 | entity_2 | 2 |
Entities:
Entity 1, entity_1 22 residues - 2470.776 Da.
| 1 | GLY | ILE | VAL | GLU | GLN | CYS | CYS | THR | SER | ILE | ||||
| 2 | CYS | SER | LEU | TYR | GLN | LEU | GLU | ASN | TYR | CYS | ||||
| 3 | ASN | SER |
Entity 2, entity_2 31 residues - 3606.224 Da.
| 1 | PHE | VAL | LYS | GLN | HIS | LEU | CYS | GLY | SER | HIS | ||||
| 2 | LEU | VAL | GLU | ALA | LEU | TYR | LEU | VAL | CYS | GLY | ||||
| 3 | GLU | ARG | GLY | PHE | PHE | TYR | THR | PRO | LYS | THR | ||||
| 4 | ARG |