BMRB Entry 34396

Title:
Structure of pore-forming amyloid-beta tetramers
Deposition date:
2019-04-23
Original release date:
2019-09-30
Authors:
Bardiaux, B.; Ciudad, S.; Carulla, N.
Citation:

Citation: Ciudad, Sonia; Puig, Eduard; Botzanowski, Thomas; Meigooni, Moeen; Arango, Andres; Do, Jimmy; Mayzel, Maxim; Bayoumi, Mariam; Chaignepain, Stephane; Maglia, Giovanni; Cianferani, Sarah; Orekhov, Vladislav; Tajkhorshid, Emad; Bardiaux, Benjamin; Carulla, Natalia. "Abeta(1-42) Tetramer and Octamer Structures Reveal Edge Conductivity Pores as a Mechanism for Membrane Damage"  Nat. Commun. 11, 3014-3014 (2020).
PubMed: 32541820

Assembly members:

Assembly members:
entity_1, polymer, 42 residues, 4520.087 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: DAEFRHDSGYEVHHQKLVFF AEDVGSNKGAIIGLMVGGVV IA

Data sets:
Data typeCount
13C chemical shifts368
15N chemical shifts132
1H chemical shifts132

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1entity_1, 11
2entity_1, 21
3entity_1, 31
4entity_1, 41

Entities:

Entity 1, entity_1, 1 42 residues - 4520.087 Da.

1   ASPALAGLUPHEARGHISASPSERGLYTYR
2   GLUVALHISHISGLNLYSLEUVALPHEPHE
3   ALAGLUASPVALGLYSERASNLYSGLYALA
4   ILEILEGLYLEUMETVALGLYGLYVALVAL
5   ILEALA

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks