BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 34414

Title: a9 PEPTIDE   PubMed: 31749266

Deposition date: 2019-06-17 Original release date: 2019-10-24

Authors: De Luca, S.; Verdoliva, V.; Saviano, M.; Fattorusso, R.; Diana, D.

Citation: De Luca, S.; Verdoliva, V.; Saviano, M.; Fattorusso, R.; Diana, D.. "SPR and NMR characterization of the molecular interaction between A9 peptide and a model system of HER2 receptor: A fragment approach for selecting peptide structures specific for their target"  J. Pept. Sci. 26, e3231-e3231 (2019).

Assembly members:
entity_1, polymer, 9 residues, 1003.065 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
entity_1: QDVNTAVAW

Data sets:
Data typeCount
1H chemical shifts58

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1entity_11

Entities:

Entity 1, entity_1 9 residues - 1003.065 Da.

1   GLNASPVALASNTHRALAVALALATRP

Samples:

sample_1: A9 PEPTIDE 1 mM

sample_conditions_1: ionic strength: 1 mM; pH: 6.8; pressure: 1 atm; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
2D 1H-1H NOESYsample_1isotropicsample_conditions_1
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
2D 1H-1H COSYsample_1isotropicsample_conditions_1

Software:

VNMR, Varian - collection

CARA, Keller and Wuthrich - chemical shift assignment

CYANA, Guntert, Mumenthaler and Wuthrich - structure calculation

NMR spectrometers:

  • Varian INOVA 600 MHz