BMRB Entry 34442

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PDB ID: 6t3i
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR34442
MolProbity Validation Chart

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Title:
Solution structure of the HRP2 IBD
Deposition date:
2019-10-11
Original release date:
2020-11-12
Authors:
Veverka, V.
Citation:

Citation: Van Belle, Siska; El Ashkar, Sara; Cermakova, Katerina; Matthijssens, Filip; Goossens, Steven; Canella, Alessandro; Hodges, Courtney; Christ, Frauke; De Rijck, Jan; Van Vlierberghe, Pieter; Veverka, Vaclav; Debyser, Zeger. "Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival"  Cells 10, 192-192 (2021).
PubMed: 33477970

Assembly members:

Assembly members:
entity_1, polymer, 86 residues, 9675.237 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: AASPSVEEKLQKLHSEIKFA LKVDSPDVKRCLNALEELGT LQVTSQILQKNTDVVATLKK IRRYKANKDVMEKAAEVYTR LKSRGS

Data sets:
Data typeCount
13C chemical shifts384
15N chemical shifts85
1H chemical shifts629

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1unit_11

Entities:

Entity 1, unit_1 86 residues - 9675.237 Da.

1   ALAALASERPROSERVALGLUGLULYSLEU
2   GLNLYSLEUHISSERGLUILELYSPHEALA
3   LEULYSVALASPSERPROASPVALLYSARG
4   CYSLEUASNALALEUGLUGLULEUGLYTHR
5   LEUGLNVALTHRSERGLNILELEUGLNLYS
6   ASNTHRASPVALVALALATHRLEULYSLYS
7   ILEARGARGTYRLYSALAASNLYSASPVAL
8   METGLULYSALAALAGLUVALTYRTHRARG
9   LEULYSSERARGGLYSER

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