BMRB Entry 34510

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PDB ID: 6yhx
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR34510
MolProbity Validation Chart

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Title:
Solution NMR Structure of APP TMD I45T mutant
Deposition date:
2020-03-31
Original release date:
2020-12-04
Authors:
Silber, M.; Muhle-Goll, C.
Citation:

Citation: Silber, M.; Hitzenberger, M.; Zacharias, M.; Muhle-Goll, C.. "Altered Hinge Conformations in APP Transmembrane Helix Mutants May Affect Enzyme-Substrate Interactions of gamma-secretase"  ACS Chem. Neurosci. 11, 4426-4433 (2020).
PubMed: 33232115

Assembly members:

Assembly members:
entity_1, polymer, 30 residues, 3058.871 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: SNKGAIIGLMVGGVVIATVT VITLVMLKKK

Data sets:
Data typeCount
13C chemical shifts94
1H chemical shifts216

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1unit_11

Entities:

Entity 1, unit_1 30 residues - 3058.871 Da.

1   SERASNLYSGLYALAILEILEGLYLEUMET
2   VALGLYGLYVALVALILEALATHRVALTHR
3   VALILETHRLEUVALMETLEULYSLYSLYS