BMRB Entry 34567

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PDB ID: 7asy
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR34567
MolProbity Validation Chart

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Title:
Transmembrane helix of tumor necrosis factor alpha in trifluorethanol
Deposition date:
2020-10-28
Original release date:
2020-12-01
Authors:
Guschtschin-Schmidt, N.; Muhle-Goll, C.
Citation:

Citation: Spitz, C.; Schlosser, C.; Guschtschin-Schmidt, N.; Stelzer, W.; Menig, S.; Gotz, A.; Haug-Kroper, M.; Scharnagl, C.; Langosch, D.; Muhle-Goll, C.; Fluhrer, R.. "Increased helical flexibility of the TNFalpha transmembrane domain enhances non-canonical shedding by SPPL2a"  iScience 23, 101775-101775 (2020).

Assembly members:

Assembly members:
entity_1, polymer, 33 residues, 3701.497 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: RRCLFLSLFSFLIVAGATTL FCLLHFGVIGPQR

Data sets:
Data typeCount
13C chemical shifts92
1H chemical shifts190

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1unit_11

Entities:

Entity 1, unit_1 33 residues - 3701.497 Da.

1   ARGARGCYSLEUPHELEUSERLEUPHESER
2   PHELEUILEVALALAGLYALATHRTHRLEU
3   PHECYSLEULEUHISPHEGLYVALILEGLY
4   PROGLNARG