BMRB Entry 34737

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PDB ID: 8a6i
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR34737
MolProbity Validation Chart

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Title:
Structure of the low complexity domain of TDP-43 (fragment 309-350) with methionine sulfoxide modifications
Deposition date:
2022-06-17
Original release date:
2023-01-30
Authors:
Carrasco, J.; Anton, R.; Pantoja-Uceda, D.; Laurents, D.; Oroz, J.
Citation:

Citation: Carrasco, J.; Anton, R.; Valbuena, A.; Pantoja-Uceda, D.; Mukhi, M.; Hervas, R.; Laurents, D.; Gasset, M.; Oroz, J.. "Metamorphism in TDP-43 prion-like domain determines chaperone recognition"  Nat. Commun. 14, 466-466 (2023).
PubMed: 36709343

Assembly members:

Assembly members:
entity_1, polymer, 42 residues, 4331.803 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli BL21(DE3)   Vector: pET28a

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: GGXNFGAFSINPAXXAAAQA ALQSSWGXXGXLASQQNQSG PS

Data sets:
Data typeCount
13C chemical shifts136
15N chemical shifts40
1H chemical shifts214

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1unit_11

Entities:

Entity 1, unit_1 42 residues - 4331.803 Da.

1   GLYGLYMHOASNPHEGLYALAPHESERILE
2   ASNPROALAMHOMHOALAALAALAGLNALA
3   ALALEUGLNSERSERTRPGLYMHOMHOGLY
4   MHOLEUALASERGLNGLNASNGLNSERGLY
5   PROSER

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