BMRB Entry 50004

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR50004

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Title:
Backbone 1H, 13C, and 15N Chemical Shift Assignments for human Leptin
Deposition date:
2019-08-21
Original release date:
2020-09-21
Authors:
Danielsson, Jens; Noel, Jeffrey; Duggan, Brendan; Oliveberg, Mikael; Onuchic, Jose; Jennings, Patricia; Haglund, Ellinor
Citation:

Citation: Danielsson, Jens; Noel, Jeffrey Kenneth; Simien, Jennifer Michelle; Duggan, Brendan Michael; Oliveberg, Mikael; Onuchic, Jose Nelson; Jennings, Patricia Ann; Haglund, Ellinor. "The Pierced Lasso Topology Leptin has a Bolt on Dynamic Domain Composed by the Disordered Loops I and III"  J. Mol. Biol. 432, 3050-3063 (2020).
PubMed: 32081588

Assembly members:

Assembly members:
entity_1, polymer, 146 residues, 15912.08 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET-3a

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: VPIQKVQDDTKTLIKTIVTR INDISHTQSVSSKQKVTGLD FIPGLHPILTLSKMDQTLAV YQQILTSMPSRNVIQISNDL ENLRDLLHVLAFSKSCHLPE ASGLETLDSLGGVLEASGYS TEVVALSRLQGSLQDMLEQL DLSPGC

Data sets:
Data typeCount
13C chemical shifts395
15N chemical shifts137
1H chemical shifts138

Additional metadata:

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  • Samples and Experiments
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Assembly:

Entity Assembly IDEntity NameEntity ID
1leptin monomer1

Entities:

Entity 1, leptin monomer 146 residues - 15912.08 Da.

1   VALPROILEGLNLYSVALGLNASPASPTHR
2   LYSTHRLEUILELYSTHRILEVALTHRARG
3   ILEASNASPILESERHISTHRGLNSERVAL
4   SERSERLYSGLNLYSVALTHRGLYLEUASP
5   PHEILEPROGLYLEUHISPROILELEUTHR
6   LEUSERLYSMETASPGLNTHRLEUALAVAL
7   TYRGLNGLNILELEUTHRSERMETPROSER
8   ARGASNVALILEGLNILESERASNASPLEU
9   GLUASNLEUARGASPLEULEUHISVALLEU
10   ALAPHESERLYSSERCYSHISLEUPROGLU
11   ALASERGLYLEUGLUTHRLEUASPSERLEU
12   GLYGLYVALLEUGLUALASERGLYTYRSER
13   THRGLUVALVALALALEUSERARGLEUGLN
14   GLYSERLEUGLNASPMETLEUGLUGLNLEU
15   ASPLEUSERPROGLYCYS

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks