BMRB Entry 50148

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR50148

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Title:
1H, 15N, and 13C backbone chemical shift assignments for the first bromodomain of BRD3 (BRD3-BD1)
Deposition date:
2019-12-31
Original release date:
2021-08-12
Authors:
Patel, Karishma; Mackay, Joel; Solomon, Paul
Citation:

Citation: Patel, Karishma; Solomon, Paul; Walshe, James; Ford, Daniel; Wilkinson-White, Lorna; Payne, Richard; Low, Jason; Mackay, Joel. "BET-Family Bromodomains Can Recognize Diacetylated Sequences from Transcription Factors Using a Conserved Mechanism"  Biochemistry 60, 648-662 (2021).
PubMed: 33620209

Assembly members:

Assembly members:
The first bromodomain of BRD3, polymer, 128 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Rat   Taxonomy ID: 10116   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Rattus norvegicus

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pGEX-6P

Entity Sequences (FASTA):

Entity Sequences (FASTA):
The first bromodomain of BRD3: QPLGSEVSNPSKPGRKTNQL QYMQNVVVKTLWKHQFAWPF YQPVDAIKLNLPDYHKIIKN PMDMGTIKKRLENNYYWSAS ECMQDFNTMFTNCYIYNKPT DDIVLMAQALEKIFLQKVAQ MPQEEVEL

Data sets:
Data typeCount
13C chemical shifts244
15N chemical shifts112
1H chemical shifts112

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1The first bromodomain of BRD31

Entities:

Entity 1, The first bromodomain of BRD3 128 residues - Formula weight is not available

1   GLNPROLEUGLYSERGLUVALSERASNPRO
2   SERLYSPROGLYARGLYSTHRASNGLNLEU
3   GLNTYRMETGLNASNVALVALVALLYSTHR
4   LEUTRPLYSHISGLNPHEALATRPPROPHE
5   TYRGLNPROVALASPALAILELYSLEUASN
6   LEUPROASPTYRHISLYSILEILELYSASN
7   PROMETASPMETGLYTHRILELYSLYSARG
8   LEUGLUASNASNTYRTYRTRPSERALASER
9   GLUCYSMETGLNASPPHEASNTHRMETPHE
10   THRASNCYSTYRILETYRASNLYSPROTHR
11   ASPASPILEVALLEUMETALAGLNALALEU
12   GLULYSILEPHELEUGLNLYSVALALAGLN
13   METPROGLNGLUGLUVALGLULEU

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks