BMRB Entry 50552

Title:
structure of SRSF1 RRM1 bound to RNA (AACAAA)
Deposition date:
2020-11-09
Original release date:
2020-12-10
Authors:
Clery, Antoine
Citation:

Citation: Clery, Antoine; Krepl, Miroslav; Nguyen, Cristina; Moursy, Ahmed; Jorjani, Hadi; Katsantoni, Maria; Okoniewski, Michal; Mittal, Nitish; Zavolan, Mihaela; Sponer, Jiri; Allain, Frederic. "Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing"  Nat. Commun. 12, 428-428 (2021).
PubMed: 33462199

Assembly members:

Assembly members:
entity_1, polymer, 6 residues, Formula weight is not available
entity_2, polymer, 84 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: obtained from a vendor

Entity Sequences (FASTA):

Data sets:
Data typeCount
13C chemical shifts213
15N chemical shifts74
1H chemical shifts550

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1subunit11
2subunit22

Entities:

Entity 1, subunit1 6 residues - Formula weight is not available

1   AACAAA

Entity 2, subunit2 84 residues - Formula weight is not available

1   VALILEARGGLYPROALAGLYASNASNASP
2   CYSARGILETYRVALGLYASNLEUPROPRO
3   ASPILEARGTHRLYSASPILEGLUASPVAL
4   PHESERLYSTYRGLYALAILEARGASPILE
5   ASPLEULYSASNARGARGGLYGLYPROPRO
6   PHEALAPHEVALGLUPHEGLUASPPROARG
7   ASPALAGLUASPALAVALSERGLYARGASP
8   GLYTYRASPTYRASPGLYTYRARGLEUARG
9   VALGLUPHEPRO

Related Database Links:

PDB 6HPJ