BMRB Entry 50567

Chem Shift validation: AVS_anomalous, AVS_full
BMRB Entry DOI: doi:10.13018/BMR50567

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Title:
Structure of PCSK9 antagonist P9-38
Deposition date:
2020-11-11
Original release date:
2020-11-24
Authors:
Tombling, Benjamin
Citation:

Citation: Tombling, Benjamin; Lammi, Carmen; Lawrence, Nicole; Gilding, Edward; Grazioso, Giovanni; Craik, David; Wang, Conan. "Bioactive cyclization optimizes the affinity of a proprotein convertase subtilisin/kexin type 9 (PCSK9) peptide inhibitor"  J. Med. Chem. 64, 2523-2533 (2021).
PubMed: 33356222

Assembly members:

Assembly members:
entity_1, polymer, 22 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pComb3

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: CTVFTSWEEYLDWNNLHPRN SC

Data sets:
Data typeCount
13C chemical shifts54
15N chemical shifts21
1H chemical shifts139

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1P9-381

Entities:

Entity 1, P9-38 22 residues - Formula weight is not available

1   CYSTHRVALPHETHRSERTRPGLUGLUTYR
2   LEUASPTRPASNASNLEUHISPROARGASN
3   SERCYS

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks