BMRB Entry 50584

Title:
Ebola Virus Glycoprotein Interacts with Cholesterol to Enhance Membrane Fusion and Cell Entry, wt
Deposition date:
2020-11-19
Original release date:
2020-12-22
Authors:
Lee, Jinwoo; Liang, Binyong; Tamm, Lukas
Citation:

Citation: Lee, Jinwoo; Kreutzberger, Alex; Odongo, Laura; Nelson, Elizabeth; Nyenhuis, David; Kiessling, Volker; Liang, Binyong; Cafiso, David; White, Judith; Tamm, Lukas. "Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry"  Nat. Struct. Mol. Biol. 28, 181-189 (2021).
PubMed: 33462517

Assembly members:

Assembly members:
entity_1, polymer, 47 residues, 5132 Da.

Natural source:

Natural source:   Common Name: Zaire ebolavirus   Taxonomy ID: 186538   Superkingdom: Viruses   Kingdom: not available   Genus/species: Ebolavirus ZEBOV

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET24a

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: GSDKTLPDQGDNDNWWTGWR QWIPAGIGVTGVVIAVIALF AIAKFVF

Data sets:
Data typeCount
15N chemical shifts82
1H chemical shifts82

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Ebola GP2 MPER/TM1

Entities:

Entity 1, Ebola GP2 MPER/TM 47 residues - 5132 Da.

The first residue is G630, followed by S631, D632, sequentially and all the way to the last one F676.

1   GLYSERASPLYSTHRLEUPROASPGLNGLY
2   ASPASNASPASNTRPTRPTHRGLYTRPARG
3   GLNTRPILEPROALAGLYILEGLYVALTHR
4   GLYVALVALILEALAVALILEALALEUPHE
5   ALAILEALALYSPHEVALPHE

Related Database Links:

UNP Q05320
AlphaFold Q8JS62

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks