BMRB Entry 51034

Click here to enlarge.

PDB ID: 7sur
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR51034
MolProbity Validation Chart

NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry

Title:
WT Pin1 with pCDC25c ligand
Deposition date:
2021-07-28
Original release date:
2022-08-11
Authors:
Born, Alexandra; Soetbeer, Janne; Henen, Morkos; Breitgoff, Frauke; Nichols, Parker; Jeschke, Gunnar; Vogeli, Beat
Citation:

Citation: Born, Alexandra; Soetbeer, Janne; Henen, Morkos; Breitgoff, Frauke; Nichols, Parker; Jeschke, Gunnar; Vogeli, Beat. "Ligand-specific conformational change drives interdomain allostery in Pin1"  Nat. Commun. 13, 4546-4546 (2022).
PubMed: 35927276

Assembly members:

Assembly members:
entity_1, polymer, 163 residues, Formula weight is not available
entity_2, polymer, 12 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pet28a

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: MADEEKLPPGWEKRMSRSSG RVYYFNHITNASQWERPSGN SSSGGKNGQGEPARVRCSHL LVKHSQSRRPSSWRQEKITR TKEEALELINGYIQKIKSGE EDFESLASQFSDCSSAKARG DLGAFSRGQMQKPFEDASFA LRTGEMSGPVFTDSGIHIIL RTE
entity_2: XEQPLXPVTDLX

Data sets:
Data typeCount
13C chemical shifts524
15N chemical shifts168
1H chemical shifts1090

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Pin11
2pCDC25c2

Entities:

Entity 1, Pin1 163 residues - Formula weight is not available

1   METALAASPGLUGLULYSLEUPROPROGLY
2   TRPGLULYSARGMETSERARGSERSERGLY
3   ARGVALTYRTYRPHEASNHISILETHRASN
4   ALASERGLNTRPGLUARGPROSERGLYASN
5   SERSERSERGLYGLYLYSASNGLYGLNGLY
6   GLUPROALAARGVALARGCYSSERHISLEU
7   LEUVALLYSHISSERGLNSERARGARGPRO
8   SERSERTRPARGGLNGLULYSILETHRARG
9   THRLYSGLUGLUALALEUGLULEUILEASN
10   GLYTYRILEGLNLYSILELYSSERGLYGLU
11   GLUASPPHEGLUSERLEUALASERGLNPHE
12   SERASPCYSSERSERALALYSALAARGGLY
13   ASPLEUGLYALAPHESERARGGLYGLNMET
14   GLNLYSPROPHEGLUASPALASERPHEALA
15   LEUARGTHRGLYGLUMETSERGLYPROVAL
16   PHETHRASPSERGLYILEHISILEILELEU
17   ARGTHRGLU

Entity 2, pCDC25c 12 residues - Formula weight is not available

1   ACEGLUGLNPROLEUTPOPROVALTHRASP
2   LEUNH2

Related Database Links:

BMRB 27579

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks